Table 1 Baseline characteristics of study patients according to the disco-vertebral biopsies (DVB) results
Patients | Positive DVB (n = 53) | Negative DVB (n = 35) | P-value |
|---|---|---|---|
Age (years), median [IQR] | 67.0 [54.0; 80.0] | 63.0 [47.5; 76.0] | 0.31 |
Sex ratio (M/F) | 2.5 | 2.9 | 0.79 |
Immunosuppression, n (%) | 5 (9.4) | 4 (11.4) | 0.76 |
Previous spine surgery, n (%) | 8 (15.0) | 2 (5.7) | 0.19 |
PVO presentation, n (%) | |||
 Acute | 25 (47.2) | 17 (48.6) | 1.0 |
 Subacute | 6 (11.3) | 7 (20.0) | 0.26 |
 Chronic | 9 (17.0) | 4 (11.4) | 0.58 |
Previous antibiotic therapy, n (%) | 9 (17.0) | 10 (28.6) | 0.2 |
Fever, n (%) | 2 (3.8) | 1 (2.9) | 0.82 |
Biology, median [IQR] | |||
 WBC count (109/L) | 9.5 [7.4; 11.5] | 7.6 [6.2; 12.2] | 0.44 |
 CRP level (mg/L) | 47.0 [26.0; 120.0] | 26.5 [8.5;123.5] | 0.42 |
 ALP (UI/L) | 117.0 [90.0; 179.5] | 144.0 [100.0; 212.0] | 0.24 |
Biology, n (%) | |||
 WBC > 10 (109/L) | 19 (47.5) | 10 (35.7) | 0.33 |
 CRP > 50 mg/L | 19 (86.4) | 12 (42.8) | 0.77 |
 CRP > 100 mg/L | 14 (34.1) | 8 (28.6) | 0.62 |
 ALP > 118 UI/L | 20 (55.6) | 18 (64.2) | 0.48 |
Radiology, n (%) | |||
 Epidural abscess | 8 (19.5) | 5 (16.7) | 0.76 |
 Psoas abscess | 7 (17.1) | 8 (26.7) | 0.33 |
 Discal abscess | 11 (26.2) | 8 (26.7) | 0.96 |
 Paravertebral abscess | 12 (29.3) | 9 (30.0) | 0.95 |
 Vertebral endplates erosions > 50% | 16 (37.2) | 9 (28.1) | 0.41 |
 Paravertebral infiltration ≥10 mm | 22 (52.4) | 4 (13.3) | 0.0006 |
Spine Level, n (%) | |||
 Cervical | 3 (5.7) | 2 (5.7) | 1.0 |
 Thoracic | 20 (37.7) | 12 (34.3) | 0.7 |
 Lumbar | 30 (56.6) | 21 (60.0) | 0.8 |
Microbiology, n (%) | |||
 Monomicrobial infection | 41 (77.4) | NA | NA |
 Coagulase negative staphylococci | 15 (28.3) | NA | NA |
Staphylococcus aureus | 10 (18.9) | NA | NA |
Cutibacterium acnes | 7 (13.2) | NA | NA |
Escherichia coli | 3 (5.7) | NA | NA |
 Streptococci | 4 (7.5) | NA | NA |
 Anaerobes | 3 (5.7) | NA | NA |
Pseudomonas aeruginosa | 2 (3.8) | NA | NA |
 Enterococci | 1 (1.9) | NA | NA |
Klebsiella spp. | 1 (1.9) | NA | NA |