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Table 3 Influence of glucose-6-phosphate dehydrogenase on P. falciparum malaria infection in children under 3 years in Vihiga County, Kenya

From: Influence of blood group, Glucose-6-phosphate dehydrogenase and Haemoglobin genotype on Falciparum malaria in children in Vihiga highland of Western Kenya

Category Prevalence (%) SMA
n = 137
Non-SMA
n = 437
P-Valuea OR 95% CI P-Valueb
G6PD deficiency SMA
Normal 360 (62.7) 77 (56.2) 283 (64.8) 0.040 Ref
Intermediate 201 (35.0) 59 (43.1) 142 (32.5) 1.527 1.029–2.266 0.035
Deficient 13 (2.3) 1 (0.7) 12 (2.7) 0.306 0.039–2.392 0.259
  1. Prevalence in the G6PD genotypes in population studied are presented as n (percentage, %). Data shown are number (n) and proportions (%) of subjects. Odds ratios (OR) and 95% confidence intervals (95% CI) were determined using multivariate logistic regression controlling for age and sex. Non-severe malaria anaemia was used as the reference category. G6PD, glucose-6-phosphate dehydrogenase. Normal, normal G6PD. Intermediate, heterozygous G6PD. Deficient, homozygous G6PD. SMA, severe malaria aneamia; Non-SMA, non-severe malaria anaemia