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Table 1 Demographic and clinical characteristics of dengue-positive patients vs. non-dengue patients from the hospital-based fever surveillance established in Medellin, Colombia in 2012–2014

From: Epidemiology and genetic diversity of circulating dengue viruses in Medellin, Colombia: a fever surveillance study

Characteristics Dengue-positive (n = 155) Non-dengue (n = 382) p-value Total (N = 537)
Age group (years)    0.286  
 1–4 33 (21.3) 87 (22.8)   120 (22.4)
 5–9 26 (16.8) 73 (19.1)   99 (18.4)
 10–24 42 (27.1) 100 (26.2)   142 (26.4)
 25–44 31 (20.0) 63 (16.5)   94 (17.5)
 45–65 23 (14.8) 59 (15.5)   82 (15.3)
Female (%) 89 (57.4) 224 (58.6) 0.795 313 (58.3)
Mean days of fever since onset (SD) 3.72 (1.75) 3.35 (1.57) 0.017 3.45 (1.63)
Mean overall fever duration (SD) 4.85 (2.39) 4.48 (2.37) 0.111 4.59 (2.38)
Current fever at presentation 38 (24.5) 111 (29.1) 0.287 149 (27.8)
Temperature at enrollment    0.287  
 Below 38°c 117 (75.5) 271 (70.9)   388 (72.3)
  ≥ 38°c 38 (24.5) 111 (29.1)   149 (27.8)
Fever duration prior to visit    0.001  
 1–2 days 47 (30.3) 114 (29.8)   161 (30.0)
 3–4 days 52 (33.6) 183 (47.9)   235 (43.8)
 5–7 days 56 (36.1) 85 (22.3)   141 (26.3)
Prev. dengue infection (%) 5 (3.2) 15 (3.9) 0.698 20 (3.7)
YF vaccination (%) 55 (35.5) 183 (47.9) 0.009 238 (44.3)
IPD/OPD (%) 10 (6.5)/ 145 (93.6) 10 (2.6)/ 372 (97.4) 0.034 20 (3.7)/ 517 (96.3)
Clinical diagnosis
 Suspected dengue 5 (3.2) 7 (1.8) 0.150 12 (2.2)
 Undifferentiated fever 146 (94.2) 372 (97.4)   518 (96.5)
 Others 4 (2.6) 3 (0.8)   7 (1.3)
Presence of signs and symptoms (%)
 Retro-orbital pain 72 (46.5) 152 (39.8) 0.156 224 (41.7)
 Rash 27 (17.4) 43 (11.3) 0.055 70 (13.0)
 Muscle pain 90 (58.1) 213 (55.8) 0.625 303 (56.4)
 Joint pain 93 (60.0) 215 (56.3) 0.430 308 (57.4)
 Fatigue/weakness 136 (87.7) 342 (89.5) 0.549 478 (89.0)
 Headache 125 (80.7) 279 (73.0) 0.064 404 (75.2)
 Neck pain 38 (24.5) 86 (22.5) 0.618 124 (23.1)
 Ear pain 25 (16.1) 57 (14.9) 0.724 82 (15.3)
 Nasal congestion 88 (56.8) 220 (57.6) 0.862 308 (57.4)
 Rhinorrhea 88 (56.8) 214 (56.0) 0.873 302 (56.2)
 Sore Throat 65 (41.9) 176 (46.1) 0.382 241 (44.9)
 Cough 92 (59.4) 252 (66.0) 0.148 344 (64.1)
 Sputum production 47 (30.3) 131 (34.3) 0.376 178 (33.2)
 Difficulty of breathing 20 (12.9) 57 (14.9) 0.545 77 (14.3)
 Nausea & vomiting 71 (45.8) 200 (52.4) 0.169 271 (50.5)
 Diarrhea 42 (27.1) 97 (25.4) 0.683 139 (25.9)
 Abdominal pain 68 (43.9) 162 (42.4) 0.756 230 (42.8)
 Flushed face 52 (33.6) 103 (27.0) 0.127 155 (28.9)
 Gum bleeding 5 (3.2) 8 (2.1) 0.440 13 (2.4)
 Nose bleeding 14 (9.0) 46 (12.0) 0.316 60 (11.2)
 Flushed face 52 (33.6) 103 (27.0) 0.127 155 (28.9)
  1. Values are N (col. %) unless otherwise noted