Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus

Table 1 Clinical features of a cluster of patients with severe fever with thrombocytopenia syndrome

	index patient	patient 2	patient 3	patient 4
Age range	60–70	70–80	50–60	60–70
Outcome	Death	Death	Discharge	Discharge
*Symptoms and signs*
Maximal temperature, °C	39.7	39.5	39.0	39.5
Headache	Yes	Yes	Yes	Yes
Anergy	Yes	Yes	Yes	Yes
Nausea and vomiting	Yes	Yes	Yes	Yes
Bleeding	Yes	Yes	No	No
Diarrhea	Yes	Yes	Yes	No
Conjunctival congestion	Yes	Yes	No	No
Lymphadenopathy	Yes	Yes	No	No
Confusion	Yes	Yes	No	No
*Laboratory findings*
White blood cell count, × 10⁹/L	1.5	1.77	1.25	1.3
Platelets count, ×10⁹/L	25.2	28	79	57
Proteinuria	Negative	Negative	Negative	Negative
Bleeding time	No data	Delayed	Normal	Normal
Coagulation time	Delayed	Delayed	Delayed	Normal
Blood SFTSV load (TCID50/ml)	4.69 × 10⁷	1.47 × 10⁴	4.41 × 10²	2.91
Virus isolation	Yes	Yes	Yes	No

ISSN: 1471-2334