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Table 3 Clinical and laboratory details of patients with presumptive false positive results

From: In-depth analysis of T2Bacteria positive results in patients with concurrent negative blood culture: a case series

Demographics

Age range, Gender

Brief History of present illness

T2Bacteria result

Other (+) culture with other than T2-detected pathogen within 21 days

Antibiotics used/Activity against T2 detected bacterium

Relevant Radiologic Findings

Discharge Diagnosis

Patient 16

> 65, F

Nausea, vomiting, imbalance and blurry vision. No signs of infection. A TTE performed on day 4 showed a mobile echo-density on the aortic valve which was consistent with Lambl’s excrescence or vegetation and prompted BCs.

E. coli

No

None

MRI brain: Large acute infarct in the right cerebral hemisphere.

Stroke

Patient 17

50–64, F

Patient with abdominal pain and melena

E. coli

Cutibacterium acnes

None

Abdomen CT: pancreatitis with multiple pseudocysts

Alcohol-induced acute pancreatitis with pancreatic pseudocyst.

Patient 18

50–64, M

2 days PTA patient visited the ED for traumatic shoulder injury and BC was received. Admitted because BC yielded CoNS.

E. coli

No

None

Musculoskeletal shoulder injury

Patient 19

18–49, M

HIV positive on HAART treatment. (last CD4 was 450 cells/mm3) presents febrile (up to 38.8 °C) after status epilepticus.

P. aeruginosa

No

CRO, VAN/ No

Normal CT and MRI of the brain

Seizure Disorder

Patient 20

18–49, F

3 days of diffuse body rash, fever (40.4 °C) and headache.

P. aeruginosa

No

FEP, VAN, DOX/ Yes (FEP-96%)

Undiagnosed/ Possible Q Fever, Parvovirus B19, Toxoplasmosis

Patient 6

> 65, M

Fever, dysuria, sepsis

P. aeruginosaa

No

CIP/ Yes (CIP-85%)

Pyelonephritis

  1. aT2Bacteria detected 2 targeted organisms in the sample of this patient. Please also see Table 1
  2. BC Blood Culture, CIP Ciprofloxacin, CRO Ceftriaxone, CoNS Coagulase-negative Staphylococcus, CX culture, DOX Doxycycline, F Female, FEP Cefepime, HAART Highly active antiretroviral therapy, M Male, MSSA Methicillin susceptible S. aureus, PTA prior to admission, T2/BC T2 sample and the “companion” blood culture, TTE Transthoracic echocardiogram, UCX urine culture, VAN Vancomycin