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Table 3 Evolving features and outcome of bacterial meningitis in diabetic patients

From: Characteristics and outcome of spontaneous bacterial meningitis in patients with diabetes mellitus

Characteristics Diabetic Patients
(n = 106)
Other Patients
(n = 609)
P value
Neurological complications 31 (29.2) 123 (20.2) 0.210
• Coma 21 (19.8) 94 (15.4) 0.254
• Seizures
• Focal neurological deficits
• Cranial palsies
18 (17)
8 (7.5)
7 (6.6)
70 (11.5)
19 (3.1)
28 (4.6)
0.148
0.046
0.337
Systemic complications 48 (45.3) 184 (30.2) 0.024
• Acute respiratory failure 28 (26.4) 103 (16.9) 0.029
• Acute kidney failure 27 (25.5) 72 (11.8) < 0.001
• Septic shock 19 (17.9) 88 (14.4) 0.376
• Disseminated intravascular coagulation
• Rhabdomyolysis
11 (10.4)
6 (5.7)
47 (7.7)
22 (3.6)
0.677
0.286
Therapeutics
• Adequate empiric antibiotic therapy 93 (87.7) 568 (93.3) 0.109
• Dexamethasone therapy
• Vasoactive drugs
• Mechanical ventilation
• Dialysis
39 (36.8)
17 (16)
17 (16)
3 (2.8)
220 (36.1)
77 (12.6)
88 (14.4)
15 (2.5)
0.910
0.350
0.839
0.895
Outcome
• Neurological sequelae 8 (7.5) 19 (3.1) 0.046
• In-hospital mortality 27 (25.5) 97 (15.9) 0.025
  1. CI confidence interval, IQR interquartile range, SD standard deviation
  2. Values are reported as no./no. evaluated (%), unless otherwise noted