Table 3 Evolving features and outcome of bacterial meningitis in diabetic patients
From: Characteristics and outcome of spontaneous bacterial meningitis in patients with diabetes mellitus
| Characteristics |
Diabetic Patients (n = 106) |
Other Patients (n = 609) | P value |
|---|---|---|---|
| Neurological complications | 31 (29.2) | 123 (20.2) | 0.210 |
| • Coma | 21 (19.8) | 94 (15.4) | 0.254 |
|
• Seizures • Focal neurological deficits • Cranial palsies |
18 (17) 8 (7.5) 7 (6.6) |
70 (11.5) 19 (3.1) 28 (4.6) |
0.148 0.046 0.337 |
| Systemic complications | 48 (45.3) | 184 (30.2) | 0.024 |
| • Acute respiratory failure | 28 (26.4) | 103 (16.9) | 0.029 |
| • Acute kidney failure | 27 (25.5) | 72 (11.8) | < 0.001 |
| • Septic shock | 19 (17.9) | 88 (14.4) | 0.376 |
|
• Disseminated intravascular coagulation • Rhabdomyolysis |
11 (10.4) 6 (5.7) |
47 (7.7) 22 (3.6) |
0.677 0.286 |
| Therapeutics | |||
| • Adequate empiric antibiotic therapy | 93 (87.7) | 568 (93.3) | 0.109 |
|
• Dexamethasone therapy • Vasoactive drugs • Mechanical ventilation • Dialysis |
39 (36.8) 17 (16) 17 (16) 3 (2.8) |
220 (36.1) 77 (12.6) 88 (14.4) 15 (2.5) |
0.910 0.350 0.839 0.895 |
| Outcome | |||
| • Neurological sequelae | 8 (7.5) | 19 (3.1) | 0.046 |
| • In-hospital mortality | 27 (25.5) | 97 (15.9) | 0.025 |