| |
AmB
|
FLU
|
NYS
|
TEB
|
AFG
|
CFG
|
MFG
|
BUC
|
CLO
|
FLC
|
ITC
|
MIC
|
TEC
|
VRC
|
|---|
|
C. albicans
|
|
VVC
|
Range
|
0.15–32
|
0.030–128
|
0.03–32
|
0.03–256
|
0.008–0.5
|
0.008–0.5
|
0.008–0.5
|
0.015–32
|
0.015–32
|
0.06–128
|
0.015–32
|
0.015–32
|
0.015–32
|
0.015–8
|
|
GM
|
0.21
|
0.65
|
1.55
|
39.23
|
0.02
|
0.1
|
0.03
|
0.11
|
0.05
|
0.74
|
0.09
|
0.27
|
0.12
|
0.06
|
|
MIC90
|
0.5
|
4
|
8
|
256
|
0.03
|
0.25
|
0.25
|
1
|
0.25
|
4
|
1
|
4
|
2
|
0.5
|
|
RVVC
|
Range
|
0.015–32
|
0.06–128
|
0.03–32
|
0.25–256
|
0.008–0.25
|
0.008–0.5
|
0.008–0.5
|
0.015–8
|
0.015–16
|
0.06–64
|
0.015–32
|
0.015–32
|
0.015–32
|
0.015–8
|
|
GM
|
0.25
|
0.94
|
1.82
|
74.50
|
0.01
|
0.1
|
0.03
|
0.13
|
0.05
|
1.03
|
0.10
|
0.46
|
0.33
|
0.09
|
|
MIC90
|
0.6
|
4
|
8
|
256
|
0.015
|
0.25
|
0.06
|
1
|
0.5
|
4
|
0.5
|
8
|
8
|
0.5
|
|
P
|
0.813
|
0.435
|
0.770
|
0
|
0.242
|
0.7
|
0.566
|
0.736
|
0.341
|
0.14
|
0.041
|
0.053
|
0
|
0.34
|
|
C. glabrata
|
|
VVC
|
Range
|
0.03–2
|
0.06–16
|
0.03–32
|
0.25–256
|
0.015–0.5
|
0.008–0.5
|
0.008–0.5
|
0.015–16
|
0.015–16
|
0.125–128
|
0.015–32
|
0.015–16
|
0.015–32
|
0.015–32
|
|
GM
|
0.33
|
0.18
|
3.88
|
40.63
|
0.03
|
0.06
|
0.05
|
0.24
|
0.23
|
1.68
|
0.42
|
0.25
|
0.15
|
0.09
|
|
MIC90
|
1
|
1
|
8
|
256
|
0.06
|
0.25
|
0.25
|
1
|
1
|
8
|
4
|
2
|
1
|
0.25
|
|
RVVC
|
Range
|
0.03–2
|
0.06–2
|
0.03–16
|
0.25–256
|
0.008–0.06
|
0.008–0.5
|
0.008–0.5
|
0.015–8
|
0.03–4
|
0.125–128
|
0.03–32
|
0.03–32
|
0.015–32
|
0.015–32
|
|
GM
|
0.20
|
0.17
|
2.31
|
8.86
|
0.02
|
0.06
|
0.04
|
0.16
|
0.134
|
1.03
|
0.29
|
0.27
|
0.17
|
0.11
|
|
MIC90
|
0.5
|
1
|
8
|
256
|
0.03
|
0.25
|
0.25
|
1
|
1
|
16
|
2
|
4
|
2
|
0.5
|
|
P
|
0.017
|
0.366
|
0.035
|
0.015
|
0.058
|
0.68
|
0.78
|
0.87
|
0.25
|
0.1
|
1
|
0.043
|
0.683
|
0.293
|
- Note: GM geometry mean, BUC butoconazole, CLO Clotrimazole, FLC Fluconazole, ITC Itraconazole, VRC Voriconazole, MIC Miconazole, TEC Terconazole, AmB Amphotericin B, FLU Flucytosine, NYS Nystatin, TEB Terbinafine, AFG Anidulafungin, CFG Caspofungin, MFG Micafungin. The MIC GM value of C. albicans for Itraconazole, Terconazole, and Terbinafine in RVVC is higher than those in VVC. The MIC GM value of C. glabrata for Miconazole, Amphotericin B, Nystatin, Caspofungin, and Terbinafine in RVVC is higher than those in VVC
