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Table 4 Sample size to detect a minimum acceptable efficacy (p0) of 0.80 using a two-sided Exact binomial test for difference assuming alpha = 5% and power = 80%*

From: Phase II trial evaluating the clinical efficacy of cefixime for treatment of active syphilis in non-pregnant women in Brazil (CeBra)

Anticipated efficacy PSample size *Effective sample size (20% inflated) n
0.86316395
0.87225282
0.88173217
0.89131164
0.90107134
0.9188110
0.926987
0.935569
0.944860
0.954152
0.963443
0.972633
0.982633
0.991722