Table 3 Risk Factors associated with S. aureus infection: Multivariable Cox regression analysis results
From: Burden of Staphylococcus aureus infections after orthopedic surgery in Germany
Variable | Patients who experienced a SAI in the 365-day follow-up period (N = 1430) compared to patients who did not experience a SAI (N = 72,897) | ||
|---|---|---|---|
HR | 95% CI | p-value | |
Age at index | 1.02 | 1.01–1.02 | p < 0.001 |
Female sex | 0.62 | 0.56–0.70 | p < 0.001 |
Index surgery type | |||
Hip; N (%) | - Reference - | ||
Knee; N (%) | 0.84 | 0.73–0.98 | p = 0.024 |
Spine; N (%) | 0.97 | 0.86–1.10 | p = 0.686 |
CCI (12 months baseline period) | 1.13 | 1.11–1.15 | p < 0.001 |
Length of index hospitalization in days | 1.02 | 1.01–1.02 | p < 0.001 |
Complications due to prosthetic devices/ implants/grafts during index hospitalization | 1.27 | 1.05–1.54 | p = 0.012 |
Recent fractures at the location of index surgery (3 months baseline period) | 2.05 | 1.81–2.32 | p < 0.001 |
Bacterial infections (not caused by any Staphylococci) during index hospitalization | 1.38 | 1.16–1.64 | p < 0.001 |
Number of outpatient prescriptions of antibiotics (12 months baseline period) | 1.06 | 1.03–1.09 | p < 0.001 |