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Table 1 Three Types of Central Nervous System Bacillus cereus Infection

From: Survival of a case of Bacillus cereus meningitis with brain abscess presenting as immune reconstitution syndrome after febrile neutropenia – a case report and literature review-


Post-Surgical Procedure/Device Infection

Neonatal Infection

Severe Neutropenia

Risk Population

Ommaya reservoir

Premature birth: 32 (27–36) weeks

WBC count <100/uL

Post intrathecal injection

Low body weight infant:1500 (830–3760) g

Induction therapy against AML

Disease Onset

Several days after procedures

7 (1–49) days after birth

Around 10 days of neutropenia

Mode of Infection



Necrotizing meningoencephalitis



Cerebral hemorrhage

Brain abscess


Subarachnoid hemorrhage

Clinical Course and Prognosis

Responds well to antimicrobial therapy

Progresses within hours

Progresses within hours

Leads to death within days

Leads to death within days

Cerebrospinal Fluid Findings

Up to 105 cells /mm3

Around 102–3 cells /mm3

Around 102 cells /mm3

Mortality rate


75% (12/14 cases)

79% (11/14 cases)



3, 4

3, 6–14