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Table 1 Frequency distribution of genotypes/allele in the study groups

From: FcγRIIIa receptor polymorphism influences NK cell mediated ADCC activity against HIV

a. Genotype (VF variants)
526 T/G (V176F)
HIV infected
N= 63(%)
HC
N= 67(%)
HIV infected vs HC
p valueOR (95% CI)
 TT(F/F)19 (30.16)23 (34.33)1.00Reference
 TG(V/F)36 (57.14)34 (50.75)0.560.78 (0.36–1.68)
 GG(V/V)08 (12.70)10 (14.93)1.001.03 (0.34–3.14)
Allele (V176F)HIV infected
N = 126(%)
HC
N = 134(%)
HIV infected vs HC
p valueOR (95% CI)
 T(F)74 (58.73)80 (59.70)1.00Reference
 G(V)52 (41.27)54 (40.30)0.901.04 (0.63–1.71)
b. Genotype (YH variants)
428 T/C (Y158H)
HIV infected
N = 63(%)
HC
N = 67(%)
HIV infected vs HC
p valueOR (95% CI)
 TT(Y/Y)48 (76.19)23 (34.33)1.00Reference
 TC(Y/H)15 (23.81)44 (65.67)< 0.00010.16 (0.07–0.35)
 CC(H/H)0 (0)0 (0)
Allele (Y158H)HIV infected
N = 126(%)
HC
N = 134(%)
HIV infected vs HC
p valueOR (95% CI)
 T(Y)111 (88.10)90 (67.16)1.00Reference
 C(H)15 (11.90)44 (32.84)< 0.00013.62 (1.89–6.92)
  1. a: Frequency distribution of V176F and Y158H polymorphisms in HIV infected vs HIV uninfected healthy control groups. Presence of TT (F/F) for TG (V/F), GG (V/V) genotypes, T for G allele was taken as reference group for statistical analysis
  2. b: Frequency distribution of Y158H polymorphism in HIV infected vs healthy control groups. Presence of TT (Y/Y) for TC (Y/H), CC (H/H) genotypes, T for C allele was taken as reference group for statistical analysis
  3. Fisher’s exact test was applied. N = number of subjects; (%) = frequency of genotypes/alleles, OR = Odds ratio; CI = Confidence Interval. The results with significance are shown in bold