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Table 2 Capillary piperaquine concentration, stratified by treatment outcome and day

From: Piperaquine concentration and malaria treatment outcomes in Ugandan children treated for severe malaria with intravenous Artesunate or quinine plus Dihydroartemisinin-Piperaquine

DayMedian (IQR) capillary piperaquine concentration (ng/mL)
Unadjusted treatment outcomesAdjusted treatment outcomes
 Treatment Success (n = 52)Treatment Failure (n = 98)pRe-infection (n = 63)Recrudescence (n = 35)p
2126 (61.4–215.0)58.4 (30.3–105.0)0.00261.5 (34.3–105)61.5 (35.8–94.3)0.939
4110.5 (77.5–155.5)66.7 (32.4–103.0)< 0.00172.8 (38.8–106)59.4 (24.3–98.9)0.300
766.7 (41.8–81.9)34.7 (17.9–49.1)< 0.00135.3 (17.9–55.2)34.8 (18.1–45.1)0.847
2815.3 (11.3–23.6)10.8 (7.6–14.3)0.00111.4 (7.3–16.7)14.3 (8.2–18.1)0.549
3512.1 (8.2–5.6)10.4 (5.0–15.4)0.3527.9 (4.9–11.1)15.4 (13.2–22.2)0.095