Day | Median (IQR) capillary piperaquine concentration (ng/mL) | |||||
---|---|---|---|---|---|---|
Unadjusted treatment outcomes | Adjusted treatment outcomes | |||||
Treatment Success (n = 52) | Treatment Failure (n = 98) | p | Re-infection (n = 63) | Recrudescence (n = 35) | p | |
2 | 126 (61.4–215.0) | 58.4 (30.3–105.0) | 0.002 | 61.5 (34.3–105) | 61.5 (35.8–94.3) | 0.939 |
4 | 110.5 (77.5–155.5) | 66.7 (32.4–103.0) | < 0.001 | 72.8 (38.8–106) | 59.4 (24.3–98.9) | 0.300 |
7 | 66.7 (41.8–81.9) | 34.7 (17.9–49.1) | < 0.001 | 35.3 (17.9–55.2) | 34.8 (18.1–45.1) | 0.847 |
28 | 15.3 (11.3–23.6) | 10.8 (7.6–14.3) | 0.001 | 11.4 (7.3–16.7) | 14.3 (8.2–18.1) | 0.549 |
35 | 12.1 (8.2–5.6) | 10.4 (5.0–15.4) | 0.352 | 7.9 (4.9–11.1) | 15.4 (13.2–22.2) | 0.095 |