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Table 1 Compared TB-SPRINT 59-Plex Beamedex® results for rifampin and isoniazid resistance detection with BACTEC™ MGIT™ 960 system among the three sites evatuated, and Genotype®MTBDRplusbetween with BACTEC™ MGIT™ 960 system

From: Multicenter evaluation of TB-SPRINT 59-Plex Beamedex®: accuracy and cost analysis

    BACTEC™ MGIT™ 960
SRSESPPPVNPVAK*
TB-SPRINTFIOCRUZRIF n=58S21292.87074.291.3810.623
R926
INH n=69S32488.594.193.988.991.30.826
R231
UFRJRIF n=57S473701001009494.70.794
R07
INH n=83S5139096.293.194.193.90.869
R227
UFMGRIF n=78S45293.191.887.995.792.30.838
R427
INH n=89S51586.196.293.99192.10.835
R528
MTBDRplusRIF n=105S69197.210010098.5990.979
R035
INH n=105S69683.31001009294.20.868
R030
  1. RIF rifampin, INH isoniazid, S sensitive, R resistant, SE sensitivity, SP specificity, NPV negative predictive value, PPV positive predictive value, A accuracy, K kappa value; *all kappa value showed p value < 0.001. Interpretation of Kappa value: < 0.20 = poor; 0,21–0,40 = weak; 0,41–0,60 = moderated; 0,61–0,80 = good; > 0,80 = very good