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Table 2 Flow cytometry-based detection (%) of flavivirus envelope protein in subpopulations of human peripheral blood mononuclear cells after ex-vivo infectiona

From: Zika virus infects human blood mononuclear cells

DonorsPBMC subpopulations (%)
CD3+CD4+4G2+CD3+CD8+4G2+CD3CD19+4G2+CD14+4G2+
D129.526.917.068.1
D347.340.647.3zero
D40.6zero50.7NDb
D51.41.14.0NDb
D70.6zerozerozero
D9zerozerozero3.9
D14zerozerozero0.7
D15zerozero1.2zero
D16zero1.7zerozero
  1. aInfection rate was calculated by subtracting the percentage of 4G2+ cells in PBMCs who received ZIKV as compared with the background 4G2 labeling profile in PBMCs from the same donor, but that were not exposed to ZIKV (MOCK). Donors D2, D6, D8, D10, D11, D12 and D13 cells were all negative for 4G2 staining. bND = not determined, as very low amounts of these subpopulations were detected