Donors | PBMC subpopulations (%) |
---|
CD3+CD4+4G2+ | CD3+CD8+4G2+ | CD3−CD19+4G2+ | CD14+4G2+ |
---|
D1 | 29.5 | 26.9 | 17.0 | 68.1 |
D3 | 47.3 | 40.6 | 47.3 | zero |
D4 | 0.6 | zero | 50.7 | NDb |
D5 | 1.4 | 1.1 | 4.0 | NDb |
D7 | 0.6 | zero | zero | zero |
D9 | zero | zero | zero | 3.9 |
D14 | zero | zero | zero | 0.7 |
D15 | zero | zero | 1.2 | zero |
D16 | zero | 1.7 | zero | zero |
- aInfection rate was calculated by subtracting the percentage of 4G2+ cells in PBMCs who received ZIKV as compared with the background 4G2 labeling profile in PBMCs from the same donor, but that were not exposed to ZIKV (MOCK). Donors D2, D6, D8, D10, D11, D12 and D13 cells were all negative for 4G2 staining. bND = not determined, as very low amounts of these subpopulations were detected