From: Pregnancy outcomes of Q fever: prospective follow-up study on Reunion island
Adverse pregnancy outcomes | n | % | P value | Crude IRR | 95% CI | Adjusted IRRb | 95% CI |
---|---|---|---|---|---|---|---|
A. Exposure variable: Coxiella burnetii Phase 2 IgG ≥ 1:64 | |||||||
Composite outcomea | 0.004 | ||||||
In exposed | 18 / 19 | 94.7 | 1.53 | 1.30–1.80 | 1.55 | 1.31–1.84 | |
In unexposed | 99 / 160 | 61.9 | 1 | 1 | |||
Miscarriage | 0.004 | ||||||
In exposed | 10 / 19 | 52.6 | 2.34 | 1.39–3.92 | 2.33 | 1.48–3.67 | |
In unexposed | 36 / 160 | 22.5 | 1 | 1 | |||
Stillbirth | 0.287 | ||||||
In exposed | 2 / 19 | 10.5 | 2.11 | 0.48–9.23 | 1.70 | 0.43–6.70 | |
In unexposed | 8 / 160 | 5.0 | 1 | 1 | |||
Preterm birth | 0.568 | ||||||
In exposed | 5 / 19 | 26.3 | 1.24 | 0.55–2.79 | 1.38 | 0.72–2.62 | |
In unexposed | 34 / 160 | 21.3 | 1 | 1 | |||
Small-for-gestational age | 0.959 | ||||||
In exposed | 5 / 19 | 26.3 | 0.98 | 0.44–2.17 | 1.03 | 0.49–2.13 | |
In unexposed | 43 / 160 | 26.9 | |||||
B. Exposure variable: Coxiella burnetii Phase 2 IgG ≥ 1:256 or Phase 2 IgM ≥ 1:48 | |||||||
Composite outcomea | 0.168 | ||||||
In exposed | 9 / 10 | 90.0 | 1.41 | 1.11–1.78 | 1.47 | 1.15–1.89 | |
In unexposed | 108/169 | 63.9 | 1 | 1 | |||
Miscarriage | 0.070 | ||||||
In exposed | 5 / 10 | 50.0 | 2.06 | 1.04–4.05 | 1.78 | 0.94–3.39 | |
In unexposed | 41 / 169 | 24.3 | 1 | 1 | |||
Stillbirth | 0.099 | ||||||
In exposed | 2 / 10 | 20.0 | 4.23 | 1.02–17.41 | 3.19 | 0.92–11.00 | |
In unexposed | 8 / 169 | 4.7 | 1 | 1 | |||
Preterm birth | 0.456 | ||||||
In exposed | 3 / 10 | 30.0 | 1.41 | 0.52–3.80 | 1.75 | 0.71–4.31 | |
In unexposed | 36 / 169 | 21.3 | 1 | 1 | |||
Small-for-gestational age | 0.292 | ||||||
In exposed | 1 / 10 | 10.0 | 0.35 | 0.05–2.36 | 0.42 | 0.06–2.87 | |
In unexposed | 47/169 | 27.8 | 1 |