Skip to main content

Advertisement

Table 2 Adverse pregnancy outcomes associated with Q fever seropositivity in bivariate and multivariate analysis, among 179 pregnant women, Saint Pierre, Reunion island, May to October 2013

From: Pregnancy outcomes of Q fever: prospective follow-up study on Reunion island

Adverse pregnancy outcomesn%P valueCrude IRR95% CIAdjusted IRRb95% CI
A. Exposure variable: Coxiella burnetii Phase 2 IgG ≥ 1:64
 Composite outcomea  0.004    
  In exposed18 / 1994.7 1.531.30–1.801.551.31–1.84
  In unexposed99 / 16061.9 1 1 
 Miscarriage  0.004    
  In exposed10 / 1952.6 2.341.39–3.922.331.48–3.67
  In unexposed36 / 16022.5 1 1 
 Stillbirth  0.287    
  In exposed2 / 1910.5 2.110.48–9.231.700.43–6.70
  In unexposed8 / 1605.0 1 1 
 Preterm birth  0.568    
  In exposed5 / 1926.3 1.240.55–2.791.380.72–2.62
  In unexposed34 / 16021.3 1 1 
 Small-for-gestational age 0.959    
  In exposed5 / 1926.3 0.980.44–2.171.030.49–2.13
  In unexposed43 / 16026.9     
B. Exposure variable: Coxiella burnetii Phase 2 IgG ≥ 1:256 or Phase 2 IgM ≥ 1:48
 Composite outcomea  0.168    
  In exposed9 / 1090.0 1.411.11–1.781.471.15–1.89
  In unexposed108/16963.9 1 1 
 Miscarriage  0.070    
  In exposed5 / 1050.0 2.061.04–4.051.780.94–3.39
  In unexposed41 / 16924.3 1 1 
 Stillbirth  0.099    
  In exposed2 / 1020.0 4.231.02–17.413.190.92–11.00
  In unexposed8 / 1694.7 1 1 
 Preterm birth  0.456    
  In exposed3 / 1030.0 1.410.52–3.801.750.71–4.31
  In unexposed36 / 16921.3 1 1 
 Small-for-gestational age 0.292    
  In exposed1 / 1010.0 0.350.05–2.360.420.06–2.87
  In unexposed47/16927.8 1   
  1. Data are numbers, seropositive rates (%), crude and adjusted incidence rate ratios (IRR) and 95% confidence intervals (95% CI). P values are given for Pearson chi2 tests. aMiscarriage, stillbirth, or preterm birth, or small-for-gestational age. bMultivariate Poisson regression model with robust variance option adjusted on hypertensive pregnancy disorders, diabetes (gestational or pregestational), and maternal addictions (smoking or alcohol)