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Table 6 Factors associated with in-hospital mortality: univariate analysis

From: A changing profile of infective endocarditis at a tertiary hospital in China: a retrospective study from 2001 to 2018

Factor

Category

Number

Deaths

OR

95% CI

P

lower

upper

 

Basic

 Age

< 40

149

11(7.38)

0.465

0.219

0.986

0.042

 

> = 40

164

24(14.63)

  

 Sex

male

226

32(14.16)

4.619

1.376

15.501

0.007

 

female

87

3(3.45)

  

 Health care-related

yes

21

7(33.33)

4.714

1.756

12.654

0.003

 

no

292

28(9.59)

  

 Intravenous drug users

yes

51

10(19.61)

2.312

1.034

5.171

0.037

 

no

262

25(9.54)

  

Clinical findings

 Hemorrhagic stroke

yes

27

10(37.04)

6.141

2.541

14.840

< 0.001

 

no

286

25(8.74)

  

 Embolism

yes

82

15(18.29)

2.362

1.145

4.870

0.017

 

no

231

20(8.66)

  

 Ischemic stroke

yes

69

14(20.29)

2.703

1.292

5.653

0.007

 

no

244

21(8.61)

  

 Heart insufficiency

yes

182

27(14.84)

2.678

1.175

6.103

0.016

 

no

131

8(6.11)

  

 Acute congestive heart failure

yes

67

21(31.34)

7.565

3.586

15.961

< 0.001

 

no

246

14(5.69)

  

 Renal insufficiency

yes

28

12(42.86)

8.543

3.610

20.217

< 0.001

 

no

285

23(8.07)

  

 Pneumonia

yes

145

25(17.24)

3.292

1.523

7.115

0.002

 

no

168

10(5.95)

  

 Pleural effusion

yes

135

21(15.56)

2.158

1.053

4.421

0.033

 

no

178

14(7.87)

  

 Albumin

< 30 g/L

147

24(16.33)

2.747

1.297

5.848

0.007

 

> 30 g/L

166

11(6.63)

  

Microorganism

 Blood culture

Positive

181

25(13.81)

1.955

0.905

4.225

0.084

 

Negative

132

10(7.58)

  

 Staphylococcus aureus

yes

46

9(19.57)

2.255

0.980

5.188

0.051

 

no

267

26(9.74)

  

 Fungi

yes

6

3(50.00)

8.594

1.664

44.375

0.002

 

no

307

32(10.42)

  

Echocardiography

 Vegetaion

Negative

39

0(0.00)

1.146

1.096

1.200

0.036

 

Positive

181

35(19.34)

  

 Left heart

yes

199

28(14.07)

2.503

1.056

5.931

0.032

 

no

114

7(6.14)

  

 Both left and right heart

yes

9

4(44.44)

7.045

1.797

27.621

0.007

 

no

304

31(10.20)

  

 Valve type

Prosthetic

11

4(36.36)

4.995

1.384

18.029

0.027

 

Native

302

31(10.26)

  

 Surgery treatment

yes

187

9(4.81)

0.194

0.088

0.431

< 0.001

 

no

126

26(20.63)

  

 Early sugery

yes

160

6(3.75)

0.167

0.067

0.414

< 0.001

 

no

153

29(18.95)

  
  1. P value were estimated by Chi-squared tests or †Fisher exact tests