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Table 1 Documented cases reports of osteomyelitis of the pubic symphysis in peri/post-partum

From: Osteomyelitis of the pubic symphysis caused by methicillin-resistant Staphylococcus aureus after vaginal delivery: a case report and literature review

Reference

Age

Parity

Type of delivery

Clinical features

Radiological finding

Pathogen

Treatment

Outcomes

Eskridge et al. [5]

33 years

1

Vaginal delivery with shoulder dystocia required episiotomy, suprapubic pressure and McRobert’s maneuver

Pubic pain with ambulation starting 1 day after delivery; fever; leukocytosis

Diastasis of the symphysis pubis, erosion of pubic rami, vulvar edema

Staphylococcus epidermidis

Enterococcus faecalis

Intravenous (IV) ampicillin, sulbactam sodium changed to cefazolin and metronidazole

Surgical debridemen

Complete recovery

Lovisetti et al. [6]

25 years

2

Normal vaginaldelivery

Pubic pain starting 1 day after delivery; fever; ↑ erythrocyte sedimentation rate (ESR), leukocytosis

Diastasis of the symphysis \pubis, bone rarefaction, suprapubic abscess

Staphylococcus aureus

IV Mezlocillin, netilmicin

Surgical debridement

Stabilisation of the symphysis with a Hoffmann external frame

Complete recovery

Gamble et al. [7]

37 years

1

Cesarean section

Pubic pain with ambulation starting at 28 weeks of gestation; erythema and edema over the labia, mons pubis, and lower abdomen; low grade fever; normal complete blood count

Diastasis of the symphysis pubis, enhancing mass with a high T1 signal suggesting superinfected hematoma or abscess

Staphylococcus aureus

Pseudomonas aeuroginosa

Serratia marcescens

IV vancomycin, levofloxacin, metronidazole

Surgical debridement

Complete recovery

Ikpeme et al. [8]

28 years

Not reported

Normal vaginal delivery

Pubic pain starting 8 weeks after delivery; low grade fever; ↑ ESR, normal complete blood count

Diastasis of the symphysis pubis, irregular erosion, lytic lesions

Pseudomonas aeuroginosa

Antibiotics (not specified)

Surgical debridement

Complete recovery

Dunk et al. [9]

43 years

Not reported

Normal vaginal delivery

Pubic and groin pain starting 5 days after delivery, low grade fever, leukocytosis, ↑ C-protein reactive (CPR)

Reactive sclerosis, rarefaction, osteolysis and joint irregularity

Streptococcus group G

IV cefuroxime, metronidazole

Surgical debridement

Complete recovery

31 years

Not reported

Normal vaginal delivery

Pubic pain starting 12 h after delivery, fever, leukocytosis, ↑ CPR

Reactive sclerosis, rarefaction, osteolysis and joint irregularity

Staphylococcus epidermidis

IV cefuroxime

Complete recovery

Lawford et al. [10]

27 years

1

Emergency cesarean section for fetal tachycardia with decreased variability and late decelerations to the cardiotocography

Groin pain, tenderness to palpation in the right iliac fossa with signs of peritonism, marked vulvar oedema and fever starting at 37 weeks of gestation; normal complete blood count, ↑ CPR

5 cm collection surrounding the symphysis pubis with extension into the soft tissues

Staphylococcus aureus

IV ceftriaxone, metronidazole and gentamicin changed to flucloxacillin and cephazolin based on antibiogram results

Complete recovery

Froberg et al. [11]

33 years

Not reported

Normal vaginal delivery

Pubic pain starting at 12 weeks of gestation; normal complete blood count

Fluid within the symphysis, bilateral oedema of the pubic rami and bony erosions.

Staphylococcus capitis Cutibacterium acnes

IV clindamycin

Complete recovery

Current case report

39 years

3

Normal vaginal delivery

Pubic pain starting 12 hours after the delivery; fever, leukocytosis, ↑ CPR, ↑ procalcitonin

Diastasis of the symphysis pubis, tiny irregularities of articular surfaces, pseudo-capsulated fluid collection within the symphysis, joint effusion

Methicillin-resistant Staphylococcus aureus

IV piperacillin-tazobactam changed to vancomycin and levofloxacin based on antibiogram, then after 2 weeks, oral combination of levofloxacin plus rifampicin.

Complete recovery