Table 1 Clinical characteristics of index cases and household members for EV infection by RT-PCR and neutralizing antibodies
Characteristics | RT-PCR (+) | RT-PCR (−) | Neutralizing antibodies# (+) | Neutralizing antibodies# (−) |
|---|---|---|---|---|
INDEX CASES | 90 (60) | 60 (40) | 101 (71) ¥ | 41 (29) |
Symptoms | ||||
Hand blisters | 64 (72) | 25 (28) | 67 (80) | 17 (20) |
Foot blisters | 58 (73) | 22 (28) | 60 (81) | 14 (19) |
Knee blisters | 7 (58) | 5 (42) | 9 (82) | 2 (18) |
Buttocks blisters | 1 (33) | 2 (67) | 2 (67) | 1 (33) |
Mouth sores | 77 (60) | 51 (40) | 88 (73) | 33 (27) |
Fever | 89 (61) | 58 (39) | 100 (71) | 40 (29) |
Startle | 76 (63) | 44 (37) | 80 (70) | 34 (30) |
Erythema | 58 (64) | 32 (36) | 68 (79) | 18 (21) |
Fatigue | 1 (100) | 0 (0) | 1 (100) | 0 (0) |
Vomiting | 2 (40) | 3 (60) | 1 (25) | 3 (75) |
Diarrhea | 2 (50) | 2 (50) | 1(25) | 3 (75) |
Anorexia | 6 (100) | 0 (0) | 5 (100) | 0 (0) |
Severity * | ||||
1 | 4 (80) | 1 (20) | 5 (100) | 0 (0) |
2a | 84 (62) | 52 (38) | 94 (73) | 34 (27) |
2b | 1 (25) | 3 (75) | 1 (25) | 3 (75) |
3 | 1 (100) | 0 (0) | 0 (0) | 1 (100) |
HOUSEHOLD CONTACTS | 12 (2) | 569 (98) | 142 (26) ¶ | 403 (74) |
Symptoms ┴ | ||||
Illness | 0 (0) | 28 (100) | 6 (21) | 22 (79) |
Fever | 0 (0) | 11 (100) | 2 (18) | 9 (82) |
HFMD | 0 (0) | 4 (100) | 0 (0) | 4 (100) |
Rash | 0 (0) | 1 (100) | 0 (0) | 1 (100) |