Table 1 Demographic and clinical characteristics of the study population
From: Clinical prediction and diagnosis of neurosyphilis in HIV-negative patients: a case-control study
Characteristics | Total (n = 100) Median (IQR)/N (%) | Non-NS group (n = 50) Median (IQR)/N (%) | NS group (n = 50) Median (IQR)/N (%) | p value |
|---|---|---|---|---|
Age, years | 47(40–52) | 47(40–52) | 47(40–54) | 0.953 |
Gender | 0.106 | |||
Female | 25 (25.0%) | 16(32.0%) | 9(18.0%) | |
Male | 75 (75.0%) | 34(68.0%) | 41(82.0%) | |
Domicile place | 0.585 | |||
Guangdong Province | 84 (84.0%) | 41(82.0%) | 43(86.0%) | |
Other provinces | 16 (16.0%) | 9(18.0%) | 7(14.0%) | |
Marital status | 0.025 | |||
Single | 11 (11.0%) | 9(18.0%) | 2(4.0%) | |
Married | 89 (89.0%) | 41(82.0%) | 48(96.0%) | |
Occupation | 0.418 | |||
Permanent job | 58 (58.0%) | 31(62.0%) | 27(54.0%) | |
Temporary job | 42 (42.0%) | 19(38.0%) | 23(46.0%) | |
Neurological symptoms | 28 (28.3%) | 5(10.2%) | 23(46.0%) | < 0.001 |
Serum TRUST titer | 1:8 (1:4–1:16) | 1:4 (1:2–1:16) | 1:16(1:8–1:32) | < 0.001 |
Serum TPPA titer | 1:1280 (> 1:1280–1:1280) | 1:1280 (1:1280–1:1280) | > 1:1280 (> 1:1280–1:1280) | 0.006 |
Serum TP-IgM | 31(41.9%) | 9(27.3%) | 22(53.7%) | 0.022 |
CSF TRUST titer | Neg (Neg- Neg) | Neg (Neg- Neg) | 1:2 (Neg-1:4) | < 0.001 |
CSF TPPA titer | 1:640 (Neg-1:1280) | Neg (Neg-1:160) | 1:1280 (1:1280–1:1280) | < 0.001 |
CSF protein, mg/L | 365.0 (270.0–598.9) | 377.6(237.0–421.2) | 521.5 (300.5–796.0) | < 0.001 |
CSF WBC, cells/μL | 1 (0–5) | 0(0–5) | 3(0–10) | 0.005 |
CSF glucose, mmol/L | 3.61 (3.30–4.00) | 3.70 (3.35–4.00) | 3.5(3.2–3.9) | 0.036 |
CSF chlorides, mmol/L | 120.0 (117.0–122.0) | 121.0(117.8–124.5) | 118.1(115.8–122.0) | 0.009 |