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Table 2 Risk ratios for non-initiation of treatment by demographic and clinical characteristic among patient offered latent tuberculosis infection treatment. Risk ratios marked with an asterisk (*) are statistically significant. CI = confidence interval

From: The latent tuberculosis infection cascade of care in Iqaluit, Nunavut, 2012–2016

Potential Risk factor Non-initiators/category total (%) Unadjusted risk ratio (95% CI) Adjusted risk ratiob (95% CI), n = 280 patientsa
Age, years (per 5-year increase) 1.19 (1.13–1.25)* 1.17 (1.09–1.26)*
Sex
 Male 37/163 (22.7%) Reference Reference
 Female 43/163 (26.4%) 1.16 (0.79–1.70) 1.08 (0.71–1.65)
Ethnicity
 Inuit 40/242 (16.5%) Reference Reference
 Non-Inuit 27/56 (48.2%) 2.92 (1.97–4.32)* 1.52 (0.91–2.54)
Indication for TST
 Tuberculosis exposure 34/173 (19.7%) Reference Reference
 Employment screening 18/43 (41.9%) 2.13 (1.34–3.39)* 1.63 (1.00–2.65)*
 School screening 1/14 (7.1%) 0.36 (0.05–2.31) 1.11 (0.16–7.58)
 Self or physician referral 22/76 (28.9%) 1.47 (0.93–1.14) 0.99 (0.56–1.74)
Year of assessment
 2012 28/129 (21.7%) Reference
 2013 12/72 (16.7%) 0.78 (0.42–1.43)
 2014 23/71 (32.4%) 1.47 (0.92–2.36)
 2015 14/37 (37.8%) 1.74 (0.99–2.97)
 2016 3/12 (25.0%) 1.15 (0.41–3.23)
  1. aAmong the 328 patients offered treatment, complete data were available for 280. Data were missing regarding ethnicity in 29 (8.8%), year of assessment in 5 (1.5%), indication for TST in 20 (6.1%) and treatment initiation in 2 (0.6%)
  2. bModel included age, sex, ethnicity and indication for TST