Table 2 Risk ratios for non-initiation of treatment by demographic and clinical characteristic among patient offered latent tuberculosis infection treatment. Risk ratios marked with an asterisk (*) are statistically significant. CI = confidence interval
From: The latent tuberculosis infection cascade of care in Iqaluit, Nunavut, 2012–2016
Potential Risk factor | Non-initiators/category total (%) | Unadjusted risk ratio (95% CI) | Adjusted risk ratiob (95% CI), n = 280 patientsa |
|---|---|---|---|
Age, years (per 5-year increase) | – | 1.19 (1.13–1.25)* | 1.17 (1.09–1.26)* |
Sex | |||
Male | 37/163 (22.7%) | Reference | Reference |
Female | 43/163 (26.4%) | 1.16 (0.79–1.70) | 1.08 (0.71–1.65) |
Ethnicity | |||
Inuit | 40/242 (16.5%) | Reference | Reference |
Non-Inuit | 27/56 (48.2%) | 2.92 (1.97–4.32)* | 1.52 (0.91–2.54) |
Indication for TST | |||
Tuberculosis exposure | 34/173 (19.7%) | Reference | Reference |
Employment screening | 18/43 (41.9%) | 2.13 (1.34–3.39)* | 1.63 (1.00–2.65)* |
School screening | 1/14 (7.1%) | 0.36 (0.05–2.31) | 1.11 (0.16–7.58) |
Self or physician referral | 22/76 (28.9%) | 1.47 (0.93–1.14) | 0.99 (0.56–1.74) |
Year of assessment | |||
2012 | 28/129 (21.7%) | Reference | – |
2013 | 12/72 (16.7%) | 0.78 (0.42–1.43) | – |
2014 | 23/71 (32.4%) | 1.47 (0.92–2.36) | – |
2015 | 14/37 (37.8%) | 1.74 (0.99–2.97) | – |
2016 | 3/12 (25.0%) | 1.15 (0.41–3.23) | – |