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Table 1 Summary of patients with acute hepatitis due to visceral leishmaniasis and histopathology confirmation with liver biopsy.

From: Acute liver failure due to visceral leishmaniasis in Barcelona: a case report

  Age Gender Region Jaundice Hepatomegaly Splenomegaly AST (U/L) ALT (U/L) Alkaline phosph. (U/L) Gamma GT (U/L) Bilirrubin (mg/dl) PT (sec) Bone marrow Liver biopsy Outcome
Index case 55 Male Barcelona Spain No No Yes 1649 911 1107 447 12 15,6 Reactive changes, no infection Necroinflammatory changes.
Amastigotes
Alive
Bassegoda et al [6] 48 Male Barcelona Spain Yes Yes Yes 1326 645 407 545 5 15,2 Reactive changes, no infection Necroinflammatory changes. Amastigotes Alive
Singh et al I [7] 3 Male Bihar India NR Yes NR 700 800 NR NR NR 22 Amastigotes Necrosis, granuloma. Death
Singh et al II [7] 5 Male Bihar India NR NR NR 550 450 NR NR NR 18 Amastigotes Necrosis, granuloma. Alive
Singh et al III [7] 1 Female Bihar India NR NR NR 800 650 NR NR NR 20 Amastigotes Necrosis, granuloma. Death
  1. AST Aspartate aminotransferase, ALT Alanine aminotransferase, Phosph Phosphatase, GT Gamma glutamyl transferase, PT Prothrombin time, NR Not reported