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Table 1 Summary of patients with acute hepatitis due to visceral leishmaniasis and histopathology confirmation with liver biopsy.

From: Acute liver failure due to visceral leishmaniasis in Barcelona: a case report

 

Age

Gender

Region

Jaundice

Hepatomegaly

Splenomegaly

AST (U/L)

ALT (U/L)

Alkaline phosph. (U/L)

Gamma GT (U/L)

Bilirrubin (mg/dl)

PT (sec)

Bone marrow

Liver biopsy

Outcome

Index case

55

Male

Barcelona Spain

No

No

Yes

1649

911

1107

447

12

15,6

Reactive changes, no infection

Necroinflammatory changes.

Amastigotes

Alive

Bassegoda et al [6]

48

Male

Barcelona Spain

Yes

Yes

Yes

1326

645

407

545

5

15,2

Reactive changes, no infection

Necroinflammatory changes. Amastigotes

Alive

Singh et al I [7]

3

Male

Bihar India

NR

Yes

NR

700

800

NR

NR

NR

22

Amastigotes

Necrosis, granuloma.

Death

Singh et al II [7]

5

Male

Bihar India

NR

NR

NR

550

450

NR

NR

NR

18

Amastigotes

Necrosis, granuloma.

Alive

Singh et al III [7]

1

Female

Bihar India

NR

NR

NR

800

650

NR

NR

NR

20

Amastigotes

Necrosis, granuloma.

Death

  1. AST Aspartate aminotransferase, ALT Alanine aminotransferase, Phosph Phosphatase, GT Gamma glutamyl transferase, PT Prothrombin time, NR Not reported