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Fig. 1 | BMC Infectious Diseases

Fig. 1

From: Case report: whole genome sequencing based investigation of maternal-neonatal listeriosis in Sichuan, China

Fig. 1

The fetal-maternal listeriosis case diagnosis, treatment, investigation and WGS analysis. a Timeline of the maternal-neonatal listeriosis diagnosis, treatment and investigation since 10/08/2015. The diagnosis and treatment of the neonate and the mother, as well as the process of investigation are indicated in the upper, middle and lower sections of the timeline, respectively. The time points of sampling for L. monocytogenes culture are marked with arrows. Treatment and sampling locations are highlighted in red. b The phylogenetic analysis of the L. monocytogenes strains from the patient and the food products. The maximum parsimony tree was constructed with the software Mega 5.04, with 1000 bootstrap replicates. With the sequence of LM188 as the reference, the neonate-blood-source isolates (LM1 and LM2_N_blood) which were cultured on 11/08/2015, were identical with the isolates obtained from the vagina and pudenda of the mother. There was one SNP mutation in the strain (LM7) isolated from the pudenda of the mother after she had been discharged. The RTE-meat-source strain (LM8) isolated from the community market had 57 SNP differences compared to the neonate infection strain (LM1). The food source strain LM8 harbors a novel plasmid named pLM1688 (marked as a ring)

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