The first case of Acrophialophora levis-induced severe pneumonia: a case report and literature review

BMC Infectious Diseases

Table 1 The comparison of reported human cases of Acrophialophora infection

Case	Time	Countries	Gender/Age	Basic diseases	Diseases	Fungal type	Pathogen identification	Pathogen sites	Antifungal drug sensitivity	Outcome	References
1	1997	Spain	Male/67	Pulmonary fibrosis bullous emphysema; lung transplantation	Lung infection	A.fusispora	Morphological identification	Lower respiratory tract secretions	AMB Liposome, ITR	Dead	Sutton et al.
2	1998	Sudan	Female/12	Acute lymphocyte leukemia	Brain abscess	A.fusispora	Morphological identification	Cerebrospinal fluid aspirate	AMB Liposome, ITR	Survive	Al-Mohsen et al. [4]
3	2002	Portugal	Male/33	lung transplantation	Lung infection	A.fusispora	Morphological identification	Sputum, bronchoalveolar lavage fluid	VRC	Improved	Guarro et al. [4]
4	2005	India	Female/55	None	Fungal keratitis	A.fusispora	Morphological identification	Corneal scrape	FLU	Therapeutic keratoplasty rehabilitation after ineffectiveness	Guarro et al. [3]
5	2010	Taiwan	Male/60	Acquired immunodeficiency syndrom	Brain abscess	A.fusispora	Molecular diagnosis	Cerebrospinal fluid aspirate	VRC	Dead	Chia-Wen Li et al. [5]
6	2018	Japan	Male/77	Neutropenia and Prostatic Cancer	Corneal ulcer and uveitis infection	A.spp	Molecular diagnosis	Corneal scrape	AMB Liposome、ITR is not effective, then VRC was used	Cured	Watanabe Y et al. [4]
7	The current Report	China	Male/71	None	Severe pneumonia	A.levis	Molecular diagnosis	Lower respiratory tract secretions	AMB Liposome、Caspofungin	Dead

ISSN: 1471-2334