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Table 6 Summary of resistance profiles, target gene mutations and prevalence of PMQR genes

From: Chromosomal and plasmid-mediated fluoroquinolone resistance in human Salmonella enterica infection in Ghana

Serovar Study site Cip MIC (μg/ml) Coresistance Target mutations
gyrA gyrB PMQR
Typhi APH 0.12 AMPCSXTNATET Ser83Tyr Phe601Leu  
Glu133Gly   
Ile203Ser   
Typhi APH 0.03 AMPCSXTTET Glu133Gly Phe601Leu  
Ile203Ser   
Typhi APH 0.03   Glu133Gly   
Ile203Ser   
Typhi APH 0.03   Glu133Gly Phe601Leu  
Ile203Ser   
Typhi APH 0.03   Glu133Gly   
Ile203Ser   
Enteritidis KATH 0.03 AMPCSXTTET Ile203Ser   
Enteritidis KATH 0.12   Asp87Gly   
Ile203Ser   
Enteritidis KATH 0.12   Asp87Gly   
Ile203Ser   
Enteritidis KATH 0.50   Ile203Ser   qnrS
Typhimurium APH 0.03   Ile203Ser   
Typhimurium APH 0.50 AMPAMC Ile203Ser   qnrS
Typhimurium APH 0.03 AMPAMC Lys154Asn   
Typhimurium APH 0.03 AMPCSXTAMC Ile203Ser