Table 6 Summary of resistance profiles, target gene mutations and prevalence of PMQR genes
Serovar | Study site | Cip MIC (μg/ml) | Coresistance | Target mutations | ||
|---|---|---|---|---|---|---|
gyrA | gyrB | PMQR | ||||
Typhi | APH | 0.12 | AMPCSXTNATET | Ser83Tyr | Phe601Leu | Â |
Glu133Gly | Â | Â | ||||
Ile203Ser | Â | Â | ||||
Typhi | APH | 0.03 | AMPCSXTTET | Glu133Gly | Phe601Leu | Â |
Ile203Ser | Â | Â | ||||
Typhi | APH | 0.03 | Â | Glu133Gly | Â | Â |
Ile203Ser | Â | Â | ||||
Typhi | APH | 0.03 | Â | Glu133Gly | Phe601Leu | Â |
Ile203Ser | Â | Â | ||||
Typhi | APH | 0.03 | Â | Glu133Gly | Â | Â |
Ile203Ser | Â | Â | ||||
Enteritidis | KATH | 0.03 | AMPCSXTTET | Ile203Ser | Â | Â |
Enteritidis | KATH | 0.12 | Â | Asp87Gly | Â | Â |
Ile203Ser | Â | Â | ||||
Enteritidis | KATH | 0.12 | Â | Asp87Gly | Â | Â |
Ile203Ser | Â | Â | ||||
Enteritidis | KATH | 0.50 | Â | Ile203Ser | Â | qnrS |
Typhimurium | APH | 0.03 | Â | Ile203Ser | Â | Â |
Typhimurium | APH | 0.50 | AMPAMC | Ile203Ser | Â | qnrS |
Typhimurium | APH | 0.03 | AMPAMC | Lys154Asn | Â | Â |
Typhimurium | APH | 0.03 | AMPCSXTAMC | Ile203Ser | Â | Â |