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Table 1 Demographical and clinical characteristics among HCV control, spontaneous clearance and persistent infection populations

From: CD40 polymorphisms were associated with HCV infection susceptibility among Chinese population

Variables Group A (%) Group B (%) Group C (%) P
n = 1513 n = 496 n = 768
Age (years, mean ± SD) 52.65 ± 13.30 51.12 ± 13.82 51.89 ± 12.37 0.076a
Gender     0.130b
 Male 603 (39.9) 194 (39.1) 273 (35.5)  
 Female 910 (60.1) 302 (60.9) 495 (65.5)  
ALT (U/L)     < 0.001b
 < 40 1421 (94.9) 387 (78.2) 443 (57.8)  
 ≥40 77 (5.1) 108 (21.8) 323 (42.2)  
AST (U/L)     
 < 40 1422 (95.1) 394 (80.9) 454 (60.0) < 0.001b
 ≥40 74 (4.9) 93 (19.1) 303 (40.0)  
Route of infection     < 0.001b
 HD 553 (36.5) 91 (18.3) 76 (9.9)  
 IVDU 181 (12.0) 138 (27.8) 140 (18.2)  
 PBD 779 (51.5) 267 (53.9) 552 (71.9)  
HCV genotypes     < 0.001b
 1b 42 (26.3) 223 (46.1)  
 Non-1b 118 (73.7) 261 (53.9)  
  1. Abbreviations: ALT alanine transaminase, AST aspartate aminotransferase, HCV hepatitis C virus, HD hemodialysis, IVDU Intravenous drug user, PBD paid blood donors
  2. Group A: controls; Group B: spontaneous clearance subjects; Group C: persistent infection patients
  3. a P value of one-way ANOVA among three groups
  4. b P value of χ2-test among three/two groups