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Table 1 Demographical and clinical characteristics among HCV control, spontaneous clearance and persistent infection populations

From: CD40 polymorphisms were associated with HCV infection susceptibility among Chinese population

Variables

Group A (%)

Group B (%)

Group C (%)

P

n = 1513

n = 496

n = 768

Age (years, mean ± SD)

52.65 ± 13.30

51.12 ± 13.82

51.89 ± 12.37

0.076a

Gender

   

0.130b

 Male

603 (39.9)

194 (39.1)

273 (35.5)

 

 Female

910 (60.1)

302 (60.9)

495 (65.5)

 

ALT (U/L)

   

< 0.001b

 < 40

1421 (94.9)

387 (78.2)

443 (57.8)

 

 ≥40

77 (5.1)

108 (21.8)

323 (42.2)

 

AST (U/L)

    

 < 40

1422 (95.1)

394 (80.9)

454 (60.0)

< 0.001b

 ≥40

74 (4.9)

93 (19.1)

303 (40.0)

 

Route of infection

   

< 0.001b

 HD

553 (36.5)

91 (18.3)

76 (9.9)

 

 IVDU

181 (12.0)

138 (27.8)

140 (18.2)

 

 PBD

779 (51.5)

267 (53.9)

552 (71.9)

 

HCV genotypes

   

< 0.001b

 1b

–

42 (26.3)

223 (46.1)

 

 Non-1b

–

118 (73.7)

261 (53.9)

 
  1. Abbreviations: ALT alanine transaminase, AST aspartate aminotransferase, HCV hepatitis C virus, HD hemodialysis, IVDU Intravenous drug user, PBD paid blood donors
  2. Group A: controls; Group B: spontaneous clearance subjects; Group C: persistent infection patients
  3. a P value of one-way ANOVA among three groups
  4. b P value of χ2-test among three/two groups