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Table 3 Model-detected Trends in Patterns of Resistance in Enterobacteriaceae and Acinetobacter spp. from 2013 to 2017

From: Trends in resistant Enterobacteriaceae and Acinetobacter species in hospitalized patients in the United States: 2013–2017

Pathogen Class

Pathogen

Measurement

Overall (5-year) linear trend

Seasonality

Pattern

Quarterly slope (95% CI)

p

Pattern

p

Enterobacteriaceae

ESBL

Rate per 100 admissions

Increasing

0.0089 (0.0052, 0.0127)

< 0.0001

Insignificant

0.0617

% of isolates tested

Increasing

0.1510 (0.0974, 0.2045)

< 0.0001

Insignificant

0.1168

Carb-NS

Rate per 100 admissions

Increasing

0.0004 (0.0001, 0.0006)

0.0047

Insignificant

0.5075

% of isolates tested

Insignificant

0.0013 (−0.0027, 0.0052)

0.5331

Insignificant

0.1301

MDR

Rate per 100 admissions

Decreasing

−0.0022 (−.0038, −.0006)

0.0066

Insignificant

0.0501

% of isolates tested

Decreasing

−0.0273 (− 0.0499, − 0.0048)

0.0176

Q1 higher,

Q3 lower

0.0010

Acinetobacter spp.

Carb-NS

Rate per 100 admissions

Decreasing

−0.0009 (− 0.0011, − 0.0006)

< 0.0001

Insignificant

0.1421

% of isolates tested

Insignificant

−0.1075 (− 0.0904, 0.0697)

0.2345

Q1 higher,

Q3 lower

< 0.0001

MDR

Rate per 100 admissions

Decreasing

−0.0014 (− 0.0017, − 0.0010)

< 0.0001

Insignificant

0.2189

% of isolates tested

Decreasing

−0.4269 (− 0.5793, − 0.2744)

< 0.0001

Q1 higher,

Q3 lower

< 0.0001

  1. Abbreviations: Carb-NS carbapenem-nonsusceptible, CI confidence interval, ESBL extended-spectrum beta-lactamase-producing, MDR multidrug resistant, Q quarter