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Table 6 The 7 selected SNPs association with sepsis (n = 305, adjusted by sex and age)

From: Genetic variants in Forkhead box O1 associated with predisposition to sepsis in a Chinese Han population

SNP Model Genotype Normal controls Sepsis patients OR (95% CI) P value AIC BIC
rs2269715 Codominant C/C 59 (39.6%) 58 (37.18%) 1 0.888 − 445.35 − 429.95
C/G 70 (46.98%) 79 (50.64%) 1.08 (0.57, 2.04)    
G/G 19 (12.75%) 8 (5.13%) 1.16 (0.62, 2.17)    
Dominant C/C 59 (39.6%) 58 (37.18%) 1 0.91 −445.40 − 430.00
C/G-G/G 89 (60.4%) 87 (55.77%) 0.97 (0.61, 1.56)    
Recessive C/C-C/G 129 (87.25%) 137 (87.82%) 1 0.69 −445.42 −430.02
G/G 19 (12.75%) 8 (5.13%) 1.12 (0.63, 1.99)    
Overdominant C/C-G/G 78 (52.35%) 66 (42.31%) 1 0.79 −445.50 −430.10
C/G 70 (46.98%) 79 (50.64%) 0.94 (0.59, 1.49)    
rs2721068 Codominant T/T 7 (4.7%) 19 (12.18%) 1 0.028 −451.43 − 436.03
T/C 58 (38.93%) 66 (42.31%) 3.67 (1.38, 9.77)    
C/C 84 (56.38%) 71 (45.51%) 1.33 (0.78, 2.18)    
Dominant T/T 7 (4.7%) 19 (12.18%) 1 0.016 −451.24 −435.84
T/C-C/C 142 (95.3%) 137 (87.82%) 3.24 (1.25, 8.44)    
Recessive T/T-T/C 65 (43.62%) 85 (54.49%) 1 0.059 − 448.12 −432.72
C/C 84 (56.38%) 71 (45.51%) 1.57 (0.98, 2.50)    
Overdominant T/T-C/C 92 (61.07%) 90 (57.69%) 1 0.719 − 444.45 −429.05
T/C 58 (38.93%) 66 (42.31%) 0.92 (0.58, 1.45)    
rs17446614 Codominant A/A 2 (1.34%) 3 (1.92%) 1 0.061 − 452.91 − 437.51
A/G 35 (23.49%) 20 (12.82%) 0.41 (0.04, 4.58)    
G/G 110 (73.83%) 133 (85.25%) 0.48 (0.25, 0.90)    
Dominant A/A 2 (1.34%) 3 (1.92%) 1 0.545 −446.91 − 431.51
A/G-G/G 145 (97.32%) 153 (98.08%) 0.47 (0.04, 5.33)    
Recessive A/A-A/G 37 (24.84%) 23 (14.75%) 1 0.018 −453.18 −437.78
G/G 110 (73.83%) 133 (85.25%) 0.47 (0.026, 0.88)    
Overdominant A/A-G/G 112 (75.17%) 136 (87.18%) 1 0.028 −452.61 −437.21
A/G 35 (23.49%) 20 (12.82%) 1.86 (1.07, 3.23)    
  1. OR Odd ratio, CI Confidential interval, AIC Akaike’s Information Criterion, BIC Bayesian Information Criterion