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Table 1 Demographic and clinical characteristics of TOHVHP HCV group and the general population

From: HCV-infected individuals have higher prevalence of comorbidity and multimorbidity: a retrospective cohort study

Variable

TOHVHP HCV group

General population

p-value

N = 1209

N = 6045

N(%)

N(%)

Age (yrs) (mean, SD)

54.54 ± 11.42

54.54 ± 11.41

1.00

Age (yrs) (median, IQR)

56 (49–62)

56 (49–62)

1.00

Age category

 16–25

15 (1.2%)

75 (1.2%)

1.00

 26–35

77 (6.4%)

385 (6.4%)

 

 36–45

127 (10.5%)

635 (10.5%)

 

 46–55

369 (30.5%)

1845 (30.5%)

 

 56–65

464 (38.4%)

2320 (38.4%)

 

 66–75

122 (10.1%)

610 (10.1%)

 

 75+

35 (2.9%)

175 (2.9%)

 

Sex

1.00

 Male

782 (64.7%)

3910 (64.7%)

 

 Female

427 (35.3%)

2135 (35.3%)

 

Immigration status

0.49

 Canadian citizen

1056 (87.3%)

5290 (87.5%)

 

 Immigrant from HCV endemic country

54 (4.5%)

230 (3.8%)

 

 Immigrant from non-endemic country

99 (8.2%)

525 (8.7%)

 

HCV mono-infection

1151 (95.2%)

–

 

HCV-HIV co-infection

53 (4.4%)

–

 

HCV-HBV co-infection

6 (0.5%)

–

 

Time from HCV diagnosis

  < 5 years from index date

124 (10.3%)

–

 

 5 to < 10 years from index date

123 (10.2%)

–

 

 10+ years from index date

263 (21.8%)

–

 

 Missing

699 (57.8%)

–

 

Treatment statusa

 Treated and cured

690 (57.1%)

–

 

 Treated and not cured

51 (4.2%)

–

 

 Never treated

329 (27.2%)

–

 

 Missing

139 (11.4%)

  

HCV treatment type (n = 741)

 Direct acting antiviral (DAA)

563 (76.0%)

–

 

 Interferon (IFN)

178 (24.0%)

–

 

Highest fibrosis score

 1

332 (27.5%)

–

 

 2

171 (14.1%)

–

 

 3

120 (9.9%)

–

 

 4

309 (25.6%)

–

 

 Missing

277 (22.9%)

–

 

Prevalence of multimorbidity (at least two physical conditions)

361 (29.9%)

1259 (20.8%)

< 0.001

Prevalence of physical-mental health multimorbidity

299 (24.7%)

574 (9.5%)

< 0.001

  1. a 139 (11.5%) individuals could not be classified into any of the treatment status categories. Of these 33 (2.7%) were treated but had not completed their post-treatment bloodwork and cured status could not be determine, 72 (6.0%) were potentially LTFU, and 34 (2.8%) were unaccounted for (not found in either treatment database, but no record of lab test results (VL bloodwork))