Quantitative investigation of factors relevant to the T cell spot test for tuberculosis infection in active tuberculosis

Table 3 Optimal scale regression analysis of SFCs to ESAT-6 or CFP-10

Variable	Beta	Standardized	df	F	Sig.	Tolerance		Importance
Variable	Beta	coefficients Std.Error	df	F	Sig.	After transformation	Before transformation	Importance
SFCs to ESAT-6^a
Previously treated cases	0.103	0.046	1	5.110	0.024	0.948	0.948	0.095
Platelet, ×10⁹/L,	0.115	0.054	1	4.471	0.035	0.818	0.818	0.100
Prealbumin, mg/L	0.043	0.072	1	0.366	0.545	0.492	0.492	0.040
Albumin, g/L	0.080	0.094	1	0.738	0.391	0.253	0.253	0.076
Albumin-globulin ratio	−0.075	0.082	1	0.819	0.366	0.274	0.274	−0.039
Alpha-1 globulin, g/L	−0.092	0.056	1	2.630	0.106	0.725	0.725	0.072
Beta-1 globulin, g/L	−0.016	0.062	1	0.067	0.796	0.617	0.617	−0.008
CD4+ T lymphocytes, cells/μL	0.277	0.075	1	13.539	0.000	0.598	0.598	0.596
CD8+ T lymphocytes, cells/μL	0.048	0.063	1	0.588	0.444	0.658	0.658	0.069
SFCs to CFP-10^b
Age, years	−0.022	0.057	1	0.153	0.696	0.867	0.867	0.018
Platelet, ×10⁹/L,	0.027	0.068	1	0.161	0.688	0.634	0.634	0.047
Platelet distribution width, fL	−0.149	0.058	1	6.549	0.011	0.701	0.701	0.287
Prealbumin, mg/L	−0.032	0.076	1	0.179	0.672	0.539	0.539	−0.021
Albumin, g/L	0.118	0.070	1	2.830	0.093	0.488	0.488	0.131
Alpha-2 globulin, g/L	0.133	0.049	1	7.464	0.007	0.917	0.917	0.247
CD4+ T lymphocytes, cells/μL	0.115	0.071	1	2.648	0.105	0.608	0.608	0.236
CD8+ T lymphocytes, cells/μL	0.031	0.063	1	0.245	0.621	0.652	0.652	0.055

^a: R Square = 0.169; Adjusted R Square = 0.147; F = 7.884; P<0.001
^b: R Square = 0.081; Adjusted R Square = 0.061; F = 3.890; P<0.001
CFP-10 Culture filtrate protein 10 kDa, ESAT-6 Early secreted antigenic target 6 kDa, SFCs Spot-forming cells

ISSN: 1471-2334