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Table 4 Prevalence, sensitivities and specificities, PPV and NPV in confirmation of dengue infection

From: Risk prediction for severe disease and better diagnostic accuracy in early dengue infection; the Colombo dengue study

Parameters RT-PCRa test was assumed as a perfect gold standard (%) Bayesian latest class model (%)
Prevalence 65.6 (56.4–73.8) 53.0 (43.0–62.9)
RT PCRa
 Sensitivity 96.6 (90.1–99.7)
 Specificity 69.8 (55.2–82.5)
 PPV 78.4 (66.3–88.5)
 NPV 94.8 (84.7–99.5)
RT-LAMPa
 Sensitivity 73.8 (62.5–82.7) 93.4 (80.9–99.9)
 Specificity 95.2 (82.6–99.2) 99.2 (91.7–100)
 PPV 96.7 (87.6–99.4) 99.3 (92.3–100)
 NPV 65.6 (52.2–77.0) 93.1 (78.2–99.9)
NS 1 test
 Sensitivity 61.3 (49.7–71.7) 75.1 (63.2–84.9)
 Specificity 85.7 (70.8–94.1) 89.0 (77.3–96.9)
 PPV 89.1 (77.1–95.5) 88.5 (75.3–97.0)
 NPV 53.7 (41.2–65.8) 76.0 (63.5–85.8)
  1. aRT-PCR Reverse transcription and polymerase chain reaction, NS1 NS1 antigen test, RT-LAMP Reverse transcription loop-mediated isothermal amplification, PPV Positive predictive value, NPV Negative predictive value