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Table 1 Baseline characteristics of HIV participants at the first TB screening

From: Predicting the risk of pulmonary tuberculosis based on the neutrophil-to-lymphocyte ratio at TB screening in HIV-infected individuals

Variables

Category

Total cases of TB screening

TB screeninga positive for TB

TB screening negative for TB

p-value†

N = 1118

N = 54

N = 1064

Age (years)

Under 30

226 (20.2%)

9 (16.7%)

217 (20.4%)

0.71

30–39

506 (45.3%)

24 (44.4%)

482 (45.3%)

 

Over 40

386 (34.5%)

21 (38.9%)

365 (34.3%)

 

Sex

Male

510 (45.6%)

37 (68.5%)

473 (44.4%)

0.002

Female

604 (54.0%)

17 (31.5%)

587 (55.2%)

 

Missing data

4 (0.4%)

–

4 (0.4%)

 

Ethnicity

Thai

782 (69.9%)

34 (63.0%)

748 (70.3%)

0.50

Hill tribe

211 (18.9%)

13 (24.0%)

198 (18.6%)

 

Others

125 (11.2%)

7 (13.0%)

118 (11.1%)

 

Year of DCC registration

2002–2006

489 (43.7%)

22 (40.7%)

467 (43.9%)

0.48

2007–2011

500 (44.7%)

23 (42.6%)

477 (44.8%)

 

2012–2015

129 (11.6%)

9 (16.7%)

120 (11.3%)

 

CD4 (/mm3)

< 50

262 (23.4%)

20 (37.0%)

242 (22.7%)

< 0.001

50–199

292 (26.1%)

23 (42.6%)

269 (25.3%)

 

≧200

564 (50.5%)

11 (20.4%)

553 (52.0%)

 

ART

No

633 (56.6%)

41 (75.9%)

592 (55.6%)

0.008

Past/Current

335 (30.0%)

5 (9.3%)

330 (31.0%)

 

Start during follow-up

130 (11.6%)

7 (13.0%)

123 (11.6%)

 

Missing data

20 (1.8%)

1 (1.8%)

19 (1.8%)

 

TST

(Positive: > 5 mm)

Negative

981 (87.7%)

36 (66.7%)

945 (88.8%)

< 0.001

Positive

94 (8.4%)

15 (27.8%)

79 (7.4%)

 

Not tested

43 (3.9%)

3 (5.6%)

40 (3.8%)

 

Abnormal chest X ray

No

831 (74.3%)

23 (42.6%)

808 (75.9%)

< 0.001

Yes

281 (25.1%)

31 (57.4%)

250 (23.5%)

 

No tested

6 (0.5%)

–

6 (0.6%)

 

TB symptomsb

No

693 (62.0%)

13 (24.1%)

680 (63.9%)

< 0.001

At least one symptom

425 (38.0%)

41 (75.9%)

384 (36.1%)

 

Whole blood cell counts (/mm3)

Median (IQR)

5700 (4400–7100)

5970 (4800–7500)

5700 (4400–7100)

0.30

Lymphocyte counts (/mm3)

Median (IQR)

1733.7 (1176.7–2324.7)

1170.5 (752.1–1596.7)

1777.0 (1196.2–2346.8)

< 0.001

Monocyte counts (/mm3)

Median (IQR)

343.1 (234.5–485.9)

374.0 (220.0–500.9)

341.5 (235.2–483.7)

0.53

Neutrophil counts (/mm3)

Median (IQR)

2877.9 (2160.0–3939.0)

3585.9 (2880.0–5079.6)

2827.3 (2143.6–3884.8)

< 0.001

NL ratio

Median (IQR)

1.67 (1.16–2.64)

3.27 (1.99–5.41)

1.66 (1.14–2.54)

< 0.001

  1. TB Tuberculosis, ART Anti-retroviral treatment, TST Tuberculin skin test, IQR Interquartile range, NL Neutrophil to lymphocyte.
  2. aTB screening was conducted by sputum acid-fast bacilli (AFB) positive, clinical symptoms, chest X-ray, TST, and sputum culture test
  3. bTB symptoms include cough, night sweats, fever, weight loss, and hemoptysis within 4 weeks
  4. †p-values were calculated using the chi-square test for categorical variables and Wilcoxon rank-sum test for continuous variables