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Table 4 HIV-infected control patients with positive Pj PCR in serum

From: Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study

Pat CD4 cell count (cells/uL) Criteria of the PCP reference standard of this study Outcome Index tests
Respiratory symptoms Radiologic findings Hypoxia Pj analysis respiratory specimen TMP-SMX Other lung infection BG (pg/ml) Pj PCR in serum Ct value
1 100 Dry cough Unknown Unknown Unknown No No Survival > 2000 32
2 30 Dry cough Discrete interstitial opacity Unknown Unknown Prophylaxis dose No Survival 807 33
3 10 Dry cough Normal Unknown Unknown Nob No Survival < 50 39
4 80 Dyspnea Discrete GGO Unknown PCR nega No No Survival 60 38
5 50 Productive cough and dyspnea Normal No PCR posa Prophylaxis dose No Survival 177 42
6 50 No Normal No Unknown No No Survival < 50 39
  1. PCP Pneumocystis jirovecii pneumonia, Pj Pneumocystis jirovecii, TMP-SMX trimethoprim–sulfamethoxazole, BG 1,3-ß-D-glucan, Ct Cycle threshold, GGO ground glass opacity
  2. For patients where Pj analysis, radiological exam or measurement of SpO2 was not performed, the data is noted as unknown
  3. aPCR on sputum samples
  4. breceived treatment for toxoplasmosis with pyrimethamine and sulphonamide