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Table 1 Patient characteristics and laboratory data

From: Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study

  PCP no PCP
HIV-infected
(n = 26)
HIV-infected
(n = 21)
Blood donors
(n = 18)
Age, yrs., median (range) 47 (25–70) 38 (23–64) 46 (18–59)
Females, n (%) 9 (35) 10 (48) 7 (39)
CD4+ cell count, cells/uL, median (range) 35 (0–460) 50 (0–170)
Pj PCR in serum
 Patients with positive results, n (%) 26 (100) 6 (29) 0 (0)
 Ct value, n, median (range) 29 (25–40)b 38 (32–42)
BG in serum (pg/ml)
 Patients with BG ≥80 24 (96)c 6 (29) 0 (0)
 Patients with BG ≥200 23 (92)c 3 (14) 0 (0)
 BG, median (range) 1328 (50–2000)c 50 (50–2000) 50 (50–58)
  1. PCP Pneumocystis jirovecii pneumonia, Ct cycle threshold, BG 1,3-ß-D-glucan
  2. aSerum samples collected at hospital admission due to newly diagnosed HIV-infection
  3. bThe Ct values from three patients with PCP were excluded since their samples were diluted 1:2 prior to analysis
  4. cOne sample from a patient with PCP was not analyzed for BG due to insufficient volume of serum