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Table 1 Clinical features of the patients with Candida parapsilosis arthritis in the literatures

From: Recurrent arthritis caused by Candida parapsilosis: a case report and literature review

Patient No. (reference/year of publication)

Age (years) /sex

Localization of infection

Underlying conditions

Clinical manifestations

Therapy

Outcome

1 (7)/1979

64/M

Knee

Immunosuppression, intraarticular joint injections, total knee arthroplasty

Pain and swelling

Resection Arthroplasty, AMB + 5-FC for 3 months

Cured. No recurrence after 1 year of follow-up

2 (8)/1983

59/M

Shoulder

Drug abuse, hemiarthroplasty

Pain and swelling

Resection Arthroplasty, AMB followed by KZ

Cured.

3 (9)/1984

57/M

knee

End stage renal disease

Swelling

High dose of AMB for over 2 months

Remission

(defer further treatment)

4 (10)/1986

70/F

Shoulder

hemiarthroplasty

Pain and swelling

Resection Arthroplasty, AMB

Cured.

5 (10)/1986

35/M

Knee

Total knee arthroplasty

Swelling

Resection Arthroplasty, 5-FC (duration NR)

NR.

6 (11)/1993

37/M

Knee

HIV infection, Hemophilia, total knee replacement, septic arthritis

Erythema and pain

Resection arthroplasty; FZ for 6 months

Cured.

7 (12)/1998

64/M

knee

Diabetes, total knee arthroplasty

swelling

Irrigation, debridement and drainage; total synovectomy; AMB for 4 months followed by FZ for 3 months

Cured. No recurrence after 2 years of follow-up

8 (13)/2001

68/F

Knee

total knee arthroplasty

Pain

Resection arthroplasty,

FZ for 10 weeks, Reimplantation at 3 months

Cured.

9 (14)/2002

38/F

Knee

Diabetes, renal transplantation

Fever, swelling and tenderness

Arthroscopic irrigation, FZ + 5-FC for over 1 year

Cured. No recurrence after over 1 year of follow-up

10 (15)/2006

50/M

shoulder

Drug abuse, HIV infection

Pain with fistula

Debridement; caspofungin for 6 weeks

Cured.

11 (16)/2008

65/F

Knee and shoulder

Diabetes, secondary renal failure, renal transplantation

Pain, swelling and redness

FZ for 2 months

Cured. No recurrence after 6 months of follow-up

12 (17)/2010

66/M

Hip

Chronic kidney failure, previous Serratia marcescens prosthesis infection

Post-operative fistula

2-stage reimplantation; FZ for 6 months

Cured.

13 (17)/2010

77/F

Hip

Previous coagulase-negative Staphylococcus prosthesis infection

Fever and erythema 5 months after treatment for bacterial prosthesis infection

Resection arthroplasty; AMB + 5-FC for 2 weeks followed by FZ for 9 months

Cured.

14 (18)/2010

48/F

Knee

arthroscopic arthroplasty

Pain and swelling

AMB for 3 weeks followed by FZ for 6 months

Cured.

15 (19)/2012

60/F

Wrist

rheumatoid arthritis

Swelling

Surgical debridement and wrist arthrodesis; FZ for life

Cured.

16 (CR)

56/M

Knee

Diabetes, intraarticular joint injections

Pain and swelling

Surgical debridement; FZ for 1 year

Cured. No recurrence after 1 year of follow-up

  1. AMB, amphotericin B; FZ, fluconazole; 5-FC, flucytosine; KZ, ketoconazole; NR, not reported; CR, current report