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Table 5 Clinical data and outcome according to survival status in hospital

From: Clinical parameters and outcomes of necrotizing soft tissue infections secondary to gastrointestinal fistulas

  Survivors (n = 24) No-Survivors (n = 15) P
Gender, (Male), n (%) 22 (91.7) 8 (53.3) 0.028
Age (years), mean (SD) 42.5 ± 13.4 54.9 ± 19.9 0.025
BMI (kg/m 2), mean (SD) 20.7 ± 2.1 20.0 ± 1.5 0.230
APACHE score on admission, mean (SD) 10.4 ± 3.0 13.5 ± 4.0 0.013
Etiology, n (%)
 Trauma 15 (62.5) 10 (66.7) 0.792
 Tumor 5 (20.8) 4 (26.7) 0.674
 Other 3 (12.5) 2 (13.3) 0.940
Shock on admission, n (%) 10 (41.7) 11 (73.3) 0.054
Positive blood cultures, n (%) 8 (33.3) 9 (60.0) 0.102
Multiple fistulas, n (%) 6 (25.0) 10 (66.7) 0.010
The Laboratory data on admission, mean (SD)
 C-Reactive Protein (CRP) (mg/L) 92.5 ± 70.3 173.4 ± 50.5 0.001
 White blood cell count (109/L) 12.0 ± 4.0 10.4 ± 2.7 0.126
 Platelet count (109/L) 217.6 ± 56.3 110.8 ± 57.9 < 0.001
 Hemoglobin (g/dl) 96.9 ± 13.2 110.3 ± 9.7 0.001
Wound culture, n (%)
 Monomicrobial infection 8 (33.3) 2 (13.3) 0.164
 Polymicrobial infection 9 (37.5) 13 (86.7) 0.003
 Klebsiella pneumoniae 2 (8.3) 12 (80.0) < 0.001
 Fungi 0 (0) 4 (26.7) 0.008
 Multidrug-resistant organisms 7 (28.0) 11 (73.3) 0.007
Management, n (%)
 Open abdomen 5 (20.8) 3 (20.0) 0.950
 NPWT 21 (87.5) 12 (80.0) 0.528
 Hyperbaric oxygen 1 (4.2) 1 (6.7) 0.731
Source control< 48 h, n (%) 17 (63.0) 5 (33.3) 0.022
  1. Data are reported as number of patients (%) or mean ± SD. Abbreviations: BMI Body mass index, APACHE Acute physiology and chronic health evaluation score, NPWT Negative pressure wound therapy