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Table 4 Characteristics of trauma and non-trauma patients

From: Clinical parameters and outcomes of necrotizing soft tissue infections secondary to gastrointestinal fistulas

Variable

Trauma (n = 25)

Non-trauma (n = 14)

P value

Age (years), mean (SD)

41.2 ± 13.1

57.1 ± 18.5

0.003

Gender, (Male), n (%)

21 (84.0)

9 (64.3)

0.161

BMI (kg/m 2), mean (SD)

20.5 ± 2.0

20.3 ± 1.8

0.657

APACHE score on admission, mean (SD)

10.6 ± 3.0

12.9 ± 4.4

0.057

Shock on admission, n (%)

14 (56.0)

7 (50.0)

0.718

Positive blood cultures, n (%)

12 (48.0)

5 (35.7)

0.458

Multiple fistulas, n (%)

13 (52.0)

3 (21.4)

0.063

The Laboratory data on admission, mean (SD)

 C-Reactive Protein (CRP) (mg/L)

113.5 ± 76.7

136.0 ± 70.5

0.371

 White blood cell count (109/L)

11.2 ± 3.7

10.6 ± 2.4

0.615

 Platelet count (109/L)

191.7 ± 77.5

157.1 ± 71.9

0.178

 Hemoglobin (g/dl)

106.1 ± 12.6

104.4 ± 13.2

0.683

Wound culture, n (%)

 Monomicrobial infection

7 (28.0)

3 (76.9)

0.652

 Polymicrobial infection

15 (76.9)

7 (76.9)

0.546

 Klebsiella pneumoniae

11 (44.0)

5 (35.7)

0.614

 Fungi

2 (8.0)

2 (13.3)

0.535

 Multidrug-resistant organisms

13 (52.00)

5 (35.7)

0.328

Management, n (%)

 Open abdomen

6 (24.0)

2 (14.3)

0.471

 NPWT

23 (92.0)

10 (71.4)

0.088

Hyperbaric oxygen

2 (8.0)

0 (0)

0.277

Source control< 48 h, n (%)

16 (64.0)

6 (42.9)

0.201

Wound closure, n (%)

 Local flap

9 (36.0)

2 (14.3)

0.148

 Direct suture

12 (48.0)

5 (35.7)

0.458

Delayed reconstruction repair, n (%)

14 (56.0)

2 (14.3)

0.011

In-hospital stay, mean (SD)

36.4 ± 27.4

56.9 ± 64.9

0.173

ICU stay, mean (SD)

16.3 ± 11.3

25.9 ± 23.6

0.093

In-hospital mortality, n (%)

7 (28.0)

7 (50.0)

< 0.001

  1. Data are reported as number of patients (%) or mean ± SD. Abbreviations: BMI Body mass index, APACHE Acute physiology and chronic health evaluation score, NPWT Negative pressure wound therapy