Prevalence of Zika virus in blood donations: a systematic review and meta-analysis

BMC Infectious Diseases

Table 1 Characteristics and quality assessment score of 10 included literatures

Study	Author study year	Sample source	Study period (^aepidemic)	Area	Event	Number	Detection method	Viral loads	Quality score
p1	Bierlaire2014	blood collections tested prospectively and retrospectively	3 months^a	French Polynesia	42	1505	lab developed NAT assay	2.5e3–8.1e6 copies/ ml	8
p2	Chevalier2016	blood donation screening in 2 largest blood centers	4 months^a	Puerto Rico	190	21,468	Cobas Zika ID-NAT	NM	7
p3	Gake2015	blood donors from six sites representing eco-environments	2 months	Cameroon	53	1084	Euroimmun anti-Zika NS1 IgG ELISA	NM	4
p4	Williamson2016	blood donor screening at laboratories	2 months	several states of United State	5	466,834	Procleix ZIKV assay, RT-PCR, CDC IgM/IgG-ELISA	10² IU	7
p5	Borena2016	blood donors at randomly selected donation sites	3 months	Austria	4	1001	Euroimmun anti-Zika NS1 IgM/IgG ELISA	NM	6
p5.1					0	1001	RealStar zika virus RT-PCR kit 1.0
p6	Gallian2016	consecutive blood donations	5 months^a	Martinique	76	4129	RealStar Zika virus RT-PCR Kit_1.1	2.1–6.5log10 copies/ml	6
p7	Slavov2016	volunteer blood donors	7 months^a	Brazil	37	1393	In-house method RNA test	mean 7714 copies/ml	8
p8	Kuehnert2016	screened blood donations	2 months^a	Puerto Rico	68	12,777	Cobas Zika NAT assay	NM	4
p9	Adams2016	screened blood donations	3 months^a	Puerto Rico	143	18,163	Cobas Zika NAT assay	NM	4
p10	Aubry2013	volunteer blood donors	27 months	French Polynesia	5	593	self-developed indirect IgG ELISA	NM	5

ISSN: 1471-2334