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Table 5 HCV-related health issues

From: Hepatitis C virus infection in Irish drug users and prisoners – a scoping review

  Date and author Setting Sample (n) Data collection Design Main results
[80] 2001 Goulding et al Dublin Single-site Hospital Patients with chronic HCV infection (77; m = 17; PWID = 25)   Cross-sectional Prevalence of rheumatological disease, anxiety and depression and relationship to mode of acquisition Anxiety and depression scores were significantly higher in IVDUs (P = 0.005) compared with controls.
[82] 2005 Golden et al Dublin Single-site Hospital HCV infected patients awaiting interferon treatment (90; m = 67; 47% PWID)   Prevalence of mood disorder and associated risks using a self-completed structured questionnaire Depressive disorders:
• 1-month prevalence = 21% (72% previously undiagnosed)
• Current MMT strongly associated with risk of depression (OR, 5.0; 95% CI, 1.08–23.0).
• After adjustment for age and sex, depression was associated with poorer work and social adjustment, lower acceptance of illness, higher illness stigma, poorer reported thinking and concentration, and higher levels of subjective physical symptoms (all P < .05)
Anxiety disorders:
• 1-month prevalence = 24% (86% previously undiagnosed)
• Anxiety disorders were uncorrelated with any risk factor.
[78] 2018 Mc Kiernan et al Prisons Multi-site Community Single site (hospital) HCV infected prisoners referred for HCV treatment (510; Treatment outcomes = 104) 2010–2018 Retrospective record audit Comparisons between community and prison populations SVR prison = 90.3% SVR community = 87.5% Referrals:
• Mountjoy = 265
• Wheatfield = 173
• Midlands = 33
• Portlaois =15
• Limerick =6
• Others =11