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Table 1 Demographic, health-related and laboratory characteristics of the study population, %

From: Self-reported diabetes and herpes zoster are associated with a weak humoral response to the seasonal influenza A H1N1 vaccine antigen among the elderly

Characteristics Total sample (N = 200) Female (n = 85) Male (n = 115) p value (X2 testd)
Demographic characteristics
Age groups     0.949
 65–70 y 35 35 35  
 71–75 y 37 35 37  
 76–80 y 28 29 28  
Health-related characteristics
Body Mass Indexa     0.004
 Underweight (≤18.49 kg/m2) 1.0 2.4 0  
 Normal weight (18.50–24.99 kg/m2) 36 46 28  
 Overweight (25.00–29.99 kg/m2) 45 32 55  
 Obesity (≥30.00 kg/m2) 18 20 17  
Hypertensionb     0.645
 Yes 56 54 57  
 No 44 46 43  
Heart attackc     0.511
 Yes 6.0 4.7 7.0  
 No 93 94 92  
 Don’t know 0.50 0 0.87  
 Missing values 0.50 1.2 0  
Cancerc     0.481
 Yes 20 18 22  
 No 80 81 77  
 Don’t know 0 0 0  
 Missing values 0 1.2 0.87  
Diabetes mellitusc     0.875
 Yes 7.5 7.1 7.8  
 No 92 91 92  
 Don’t know 0.50 1.2 0  
 Missing values 0 1.2 0  
Herpes zosterc     0.404
 Yes 18 20 16  
 No 79 77 82  
 Don’t know 2.0 1.2 2.6  
 Missing values 1.0 2.4 0  
Self-perceived health statusc     0.071
 Poor 0 0 0  
 Fair 9.0 12 7.0  
 Good 64 64 64  
 Very good 21 15 25  
 Excellent 4.0 7.1 1.7  
 Missing values 2.0 2.4 1.7  
Ever vaccinated against influenzac     0.112
 Yes 78 80 74  
 No 21 17 24  
 Don’t know 1.0 2.4 0  
 Missing values 1.5 1.2 1.7  
Laboratory parameters (mean ± SD)
 WBC count [x 109L]
(normal values)
6.66 ± 1.70 6.91 ± 1.83 6.48 ± 1.59 0.08 e
(3.5–11) (3.5–11)
 Neutrophils [x 109L]
(normal values)
4.03 ± 1.42 4.18 ± 1.55 3.93 ± 1.30 0.228 e
(2.0–7.0) (2.0–7.0)
 Monocytes [x 109L]
(normal values)
0.58 ± 0.17 0.57 ± 0.16 0.59 ± 0.17 0.436 e
(0.2–1.0) (0.2–1.0)
 Lymphocytes [x 109L]
(normal values)
1.89 ± 0.89 1.97 ± 0.69 1.83 ± 1.01 0.247 e
(1.0–3.0) (1.0–3.0)
 Erythrocytes [x 1012L]
(normal values)
4.81 ± 0.40 4.70 ± 0.39 4.89 ± 0.40 0.001 e
(3.90–5.00) (4.32–5.72)
 Haemoglobin [g/dL]
(normal values)
14.57 ± 1.26 13.95 ± 1.04 15.02 ± 1.22 < 0.0001 e
(12.0–15.5) (13.5–17.5)
 Thrombocytes [tsd/μL]
(normal values)
225.6 ± 54.1 256.2 ± 53.6 202.8 ± 42.0 < 0.0001 e
(150–450) (150–450)
CMV-specific IgG     0.555
 Negative 45 44 46  
 0.45–5.00 IU/mL 6.0 3.5 7.8  
 5.00–15.00 IU/mL 25 26 24  
 > 15.00 IU/mL 24 27 23  
  1. a Weight and height were measured at the study center (see Methods). Body Mass Index (BMI) was calculated using the formula “weight/height2” (kg/m2)
  2. b Blood pressure was measured at the study center (see Methods). Hypertension was defined as a systolic or diastolic blood pressure ≥ 140 mmHg and/or 90 mmHg, respectively
  3. c Self-reported information
  4. d The category “Don’t know” was not considered for chi-squared test
  5. e t-test for independent data