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Table 2 Stimuli and immune response of TruCulture®

From: Immune function as predictor of infectious complications and clinical outcome in patients undergoing solid organ transplantation (the ImmuneMo:SOT study): a prospective non-interventional observational trial

TruCulture® tube Stimulus Immune response
1 Heat killed Candida albicans Whole microbe providing complex immune response, including activation of TLR6
2 Lipopolysaccharide from E.coli (LPS) Bacterial endotoxin. Activator of TLR4.
3 Resiquimod R848 Synthetic agonist of TLR7 and TLR8 (both responding to single-stranded RNA)
4 Polyinosinic:polycytidylic acid (Poly I:C) Analogue of double-stranded RNA. Activator of TLR3
5 None (negative control) Allows for assessment of in vivo activation