Table 2 Assessment of patient’s characteristics and risk factors that could be associated with multidrug-resistant Mycobacterium tuberculosis clustering of cases, considering the cases reported between 2014 and 2017
MDR-TB patient Characteristic | Unknown | Unique (n = 25) | Clustered (n = 42) | Univariate analysis | ||
|---|---|---|---|---|---|---|
n (%) | n (%) | OR (95% CI) | p-value | |||
Age group | < 45 years old | 0 | 16 (64.0) | 21 (50.0) | Ref | 0.267 |
≥45 years old | 9 (36.0) | 21 (50.0) | 1.78 (0.64–6.91) | |||
Gender | Female | 0 | 7 (28.0) | 9 (21.4) | Ref | 0.543 |
Male | 18 (72.0) | 33 (78.6) | 1.43 (0.46–4.47) | |||
Country of origin | Foreign-born | 1 | 12 (50.0) | 9 (21.4) | Ref | 0.019 |
Native | 12 (50.0) | 33 (78.6) | 3.67 (1.24–10.88) | |||
HIV status | Negative | 4 | 21 (87.5) | 27 (69.2) | Ref | 0.109 |
Positive | 3 (12.5) | 12 (30.8) | 3.11 (0.78–12.46) | |||
Alcohol abuse | No | 6 | 22 (95.7) | 26 (68.4) | Ref | 0.032 |
Yes | 1 (4.3) | 12 (31.6) | 10.15 (1.22–84.39) | |||
Injectable drug use | No | 8 | 20 (87.0) | 29 (80.6) | Ref | 0.525 |
Yes | 3 (13.0) | 7 (19.4) | 1.61 (0.37–6.98) | |||
TB treatment history | Never treated | 4 | 15 (62.5) | 25 (64.1) | Ref | 0.898 |
Previously treated | 9 (37.5) | 14 (35.9) | 0.93 (0.33–2.68) | |||
Site of disease | Pulmonary | 4 | 24 (42.9) | 32 (57.1) | n/a | n/a |
Extra-pulmonary | 0 (0.0) | 7 (100.0) | ||||