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Table 2 Univariable and multivariable linear regression model of CD4+ T lymphocytes recovery at different time points after antiretroviral therapy initiation

From: Predictive effects of body mass index on immune reconstitution among HIV-infected HAART users in China

 

12-month Increase in CD4 Cell Count

30-month Increase in CD4 Cell Count

Univariate Model

Multivariate Model

Univariate Model

Multivariate Model

Covariate

95% CI

p

95% CI

p

95% CI

p

95% CI

p

Baseline BMI (per 1 kg/m2 increase)

1.81 (− 0.11 to 3.74)

0.065

1.64 (−0.34 to 3.61)

0.104

2.29 (−0.67 to 5.25)

0.129

3.43 (0.36 to 6.49)

0.028

Sex

−7.35 (−32.68 to 17.99)

0.570

–

–

49.26 (10.11 to 88.41)

0.014

54.40 (15.24 to 93.55)

0.007

Age

−0.57 (−1.08 to − 0.06)

0.028

–

–

− 0.71 (− 1.47 to − 0.04)

0.065

−0.96 (− 1.74 to − 0.17)

0.017

Drinking

−3.02 (−15.18 to 9.15)

0.627

–

–

8.68 (−9.86 to 27.21)

0.358

–

–

Not Han race

2.68 (−14.62 to 19.97)

0.761

–

–

−5.01 (−33.15 to 23.13)

0.727

–

–

Baseline CD4 (per 100cells/μL increase)

13.70 (9.05 to 18.36)

< 0.01

10.37 (3.82 to 16.93)

0.002

8.42 (0.44 to 16.40)

0.039

–

–

CD4/CD8 ratio

95.06 (59.51 to 130.61)

< 0.01

69.07 (22.29 to 115.84)

0.004

70.63 (12.78 to 128.48)

0.017

69.48 (−1.65 to 140.61)

0.056

Baseline log10 HIV-1 RNA

11.55 (2.96 to 20.14)

0.008

29.213 (19.87 to 38.40)

< 0.01

7.53 (−6.02 to 21.09)

0.275

–

–

Virologic failure

−64.27 (−93.11 to −35.43)

< 0.01

−50.71 (−81.05 to −20.37)

0.001

− 9.18 (−45.28 to 26.91)

0.618

–

–

WHO stage

−8.94 (−15.18 to −2.70)

0.005

–

–

8.67 (−0.54 to 17.89)

0.065

18.51 (8.22 to 28.80)

< 0.01

  1. CI confidence intervals