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Table 8 Dynamics of HA and NA glycosylation for H3N2 viruses isolated from MENA region during 2009–2017. In total, glycosylation patterns of 239 HA and 132 NA sequences of H3N2 virus were analyzed. Numbers between brackets represent the percentage of sequences expressing glycosylation sequon in corresponding year while conserved glycosylation sites are indicated in bold

From: Epidemiological and genetic characterization of pH1N1 and H3N2 influenza viruses circulated in MENA region during 2009–2017

Localization of potential glycosylation sequons in HA and NA of H3N2 viruses
HA
   Amino acid position
Year Number of sequences analyzed Stem Head Stem
2009 22 8 22   63 126 133   165 246 385 483
2011 22 8 22 45(23%) 63 126 133   165 246 385 483
2012 37 8 22 45(5%) 63 126 133   165 246 385 483
2013 13 8 22 45(69%) 63 126 133   165 246 385 483
2014 40 8 22 45(92%) 63 126 133 158(5%) 165 246 385 483
2015 47 8 22 45(100%) 63 126 133 158(81%) 165 246 385 483
2016 47 8 22 45(80%) 63 126 133 158(53%) 165 246 385 483
2017 10 8 22 45(100%) 63 126 133 158(100%) 165 246 385 483
NA
Year Number of sequences analyzed Amino acid position
2009 5 61 70 86 146 234  
2011 22 61 70 86 146 234 367 (90.6%)
2012 32 61 70 86 146 234 367 (100%)
2013 8 61 70 86 146 234 367 (100%)
2014 33 61 70 86 146 234 367 (100%)
2015 23 61 70 86 146 234 367 (100%)
2016 8 61 70 86 146 234 367 (100%)