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Table 2 Demographic and clinical HIV patients and control group characteristics

From: Alterations in bacterial communities, SCFA and biomarkers in an elderly HIV-positive and HIV-negative population in western Mexico

 

HIV-negative (n = 18)

HIV-positive (n = 20)

p value

Age (years)

68 ± 5

57 ± 5

p < 0.05a

Gender

 Male

11 (61.1%)

16 (80.0%)

p = 0.209b

 Female

7 (38.9%)

4 (20.0%)

 

CD4 T cells count; cell/μL

–

409 (IQR: 279,744)

–

CD4 nadir T cells count; cell/μL

–

74 (IQR: 39,220)

–

CD4/CD8 ratio

–

0.71 (IQR: 0.37,1.16)

–

HIV-1 viral load; copies/μL

–

34 ± 9.4

–

Tobacco Use:

 No risk

3 (16.7%)

5 (25.0%)

p = 0.697b

 Moderate

4 (22.2%)

1 (5.0%)

p = 0.170b

 Moderate/intense

2 (11.1%)

1 (5.0%)

p = 0.595b

 High

1 (5.6%)

1 (5.0%)

p = 1.000b

 No consumption

8 (44.4%)

12 (60.0%)

p = 0.332b

Alcohol use

 Yes

10 (55.6%)

5 (25.0%)

p < 0.05c

 No

8 (44.4%)

15 (75.0%)

 

Drugs antecedent

 Yes

1 (5.6%)

13 (65.0%)

p < 0.05b

 No

17 (94.4%)

7 (35.0%)

 

Body Mass Index

 Normal

8 (44.4%)

11 (55.0%)

p = 0.513c

 Overweight

10 (55.6%)

9 (45.0%)

 

Waist diameter

Men

  

p = 1.000c

 <  90 cm

6 (54.5%)

8 (50.0%)

 

 ≥ 90 cm

5 (45.5%)

8 (50.0%)

 

Women

  

p = 1.000b

 <  80 cm

2 (28.6%)

1 (25.0%)

 

 ≥ 80 cm

5 (71.4%)

3 (75.0%)

 

Hypertension

 Yes

1 (5.6%)

2 (10.0%)

p = 1.000b

 No

17 (94.4%)

18 (90.0%)

 

Hypercholesterolemia

 Yes

8 (55.6%)

11 (55.0%)

p = 0.513c

 No

10 (44.4%)

8 (40.0%)

 

 Unknown

–

1 (5.0%)

 

Depression PHQ-9

 Yes

1 (5.6%)

1 (5.0%)

p = 1.000b

 No

17 (94.4%)

19 (95.0%)

 

IBS QoL

2.8 ± 1.8

2.9 ± 1.8

p = 0.860a

VACS

15.9 ± 9.3

–

 

Fragility score

 No-fragility

9 (50)

5 (25.0)

p = 0.179c

 Pre-fragility

4 (22.2)

14 (70.0)

p < 0.05c

 Fragility

5 (27.8)

1 (5.0)

p = 0.467c

Albumin; g/dL

4.1 ± 0.4

4.3 ± 0.5

p = 0.180a

hs-CRP; μg/mL

3.5 ± 2.19

2.12 ± 2.05

p < 0.05a

sCD14; ng/mL

1131.0 (887.1–1559.3)

819.7 (739.6–1030.2)

p < 0.05d

SCFAs; mM

 Total

46.17 ± 12.9

57.12 ± 13.49

p < 0.05a

 Acetic acid

3.86 ± 3.79

1.52 ± 1.9

p < 0.05a

 Propionic acid

41.07 ± 15.62

55.05 ± 14.25

p < 0.05a

 Butyric acid

0.99 ± 1.55

0.32 ± 0.41

p < 0.05a

Firmicutes/Bacteroidetes ratio

1.7 ± 0.62

2.37 ± 0.92

p < 0.05a

  1. aStudent’s t-test, bFisher exact, cChi square, dU of Mann-Whitney test
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BMC Infectious Diseases

ISSN: 1471-2334

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