| |
HIV-negative (n = 18)
|
HIV-positive (n = 20)
|
p value
|
|---|
|
Age (years)
|
68 ± 5
|
57 ± 5
|
p < 0.05a
|
|
Gender
|
|
Male
|
11 (61.1%)
|
16 (80.0%)
|
p = 0.209b
|
|
Female
|
7 (38.9%)
|
4 (20.0%)
| |
|
CD4 T cells count; cell/μL
|
–
|
409 (IQR: 279,744)
|
–
|
|
CD4 nadir T cells count; cell/μL
|
–
|
74 (IQR: 39,220)
|
–
|
|
CD4/CD8 ratio
|
–
|
0.71 (IQR: 0.37,1.16)
|
–
|
|
HIV-1 viral load; copies/μL
|
–
|
34 ± 9.4
|
–
|
|
Tobacco Use:
|
|
No risk
|
3 (16.7%)
|
5 (25.0%)
|
p = 0.697b
|
|
Moderate
|
4 (22.2%)
|
1 (5.0%)
|
p = 0.170b
|
|
Moderate/intense
|
2 (11.1%)
|
1 (5.0%)
|
p = 0.595b
|
|
High
|
1 (5.6%)
|
1 (5.0%)
|
p = 1.000b
|
|
No consumption
|
8 (44.4%)
|
12 (60.0%)
|
p = 0.332b
|
|
Alcohol use
|
|
Yes
|
10 (55.6%)
|
5 (25.0%)
|
p < 0.05c
|
|
No
|
8 (44.4%)
|
15 (75.0%)
| |
|
Drugs antecedent
|
|
Yes
|
1 (5.6%)
|
13 (65.0%)
|
p < 0.05b
|
|
No
|
17 (94.4%)
|
7 (35.0%)
| |
|
Body Mass Index
|
|
Normal
|
8 (44.4%)
|
11 (55.0%)
|
p = 0.513c
|
|
Overweight
|
10 (55.6%)
|
9 (45.0%)
| |
|
Waist diameter
|
|
Men
| | |
p = 1.000c
|
|
< 90 cm
|
6 (54.5%)
|
8 (50.0%)
| |
|
≥ 90 cm
|
5 (45.5%)
|
8 (50.0%)
| |
|
Women
| | |
p = 1.000b
|
|
< 80 cm
|
2 (28.6%)
|
1 (25.0%)
| |
|
≥ 80 cm
|
5 (71.4%)
|
3 (75.0%)
| |
|
Hypertension
|
|
Yes
|
1 (5.6%)
|
2 (10.0%)
|
p = 1.000b
|
|
No
|
17 (94.4%)
|
18 (90.0%)
| |
|
Hypercholesterolemia
|
|
Yes
|
8 (55.6%)
|
11 (55.0%)
|
p = 0.513c
|
|
No
|
10 (44.4%)
|
8 (40.0%)
| |
|
Unknown
|
–
|
1 (5.0%)
| |
|
Depression PHQ-9
|
|
Yes
|
1 (5.6%)
|
1 (5.0%)
|
p = 1.000b
|
|
No
|
17 (94.4%)
|
19 (95.0%)
| |
|
IBS QoL
|
2.8 ± 1.8
|
2.9 ± 1.8
|
p = 0.860a
|
|
VACS
|
15.9 ± 9.3
|
–
| |
|
Fragility score
|
|
No-fragility
|
9 (50)
|
5 (25.0)
|
p = 0.179c
|
|
Pre-fragility
|
4 (22.2)
|
14 (70.0)
|
p < 0.05c
|
|
Fragility
|
5 (27.8)
|
1 (5.0)
|
p = 0.467c
|
|
Albumin; g/dL
|
4.1 ± 0.4
|
4.3 ± 0.5
|
p = 0.180a
|
|
hs-CRP; μg/mL
|
3.5 ± 2.19
|
2.12 ± 2.05
|
p < 0.05a
|
|
sCD14; ng/mL
|
1131.0 (887.1–1559.3)
|
819.7 (739.6–1030.2)
|
p < 0.05d
|
|
SCFAs; mM
|
|
Total
|
46.17 ± 12.9
|
57.12 ± 13.49
|
p < 0.05a
|
|
Acetic acid
|
3.86 ± 3.79
|
1.52 ± 1.9
|
p < 0.05a
|
|
Propionic acid
|
41.07 ± 15.62
|
55.05 ± 14.25
|
p < 0.05a
|
|
Butyric acid
|
0.99 ± 1.55
|
0.32 ± 0.41
|
p < 0.05a
|
|
Firmicutes/Bacteroidetes ratio
|
1.7 ± 0.62
|
2.37 ± 0.92
|
p < 0.05a
|
- aStudent’s t-test, bFisher exact, cChi square, dU of Mann-Whitney test
