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Table 2 Independent factors associated with several markers of haemoglobin dynamics and recovery in all patients

From: The tolerability of single low dose primaquine in glucose-6-phosphate deficient and normal falciparum-infected Cambodians

Parameter Coefficient 95% confidence interval P value
Day 7 Day 0 decline in haemoglobin concentration
 D0 haemoglobin concentration −0.34 −0.45– −0.24 < 0.001
 D0 parasite count −2.69 × 10−7 −4.81 × 10−6 – −5.60 × 10− 7 0.014
 On DHAPP+ SLDPQ 0.48 0.08–0.88 0.019
Haemoglobin dynamics over 28 days
 DHAPP+SLDPQ 0.69 0.11 ─ 1.27 0.019
 Age 0.034 0.014–0.055 0.001
 Male 0.91 0.19–1.62 0.013
 Reticulocyte dynamics −0.12 − 0.17 – − 0.06 0.000
Total malaria attributable fall in haemoglobin
 Treatment failure −1.28 −2.27 – −0.029 0.012
 D7 haemoglobin concentration −0.53 −0.74 – − 0.32 < 0.001
 Male 0.99 0.004–1.99 0.049
Haemoglobin recoverya
 Male 7.2 1.3–40.0 0.025
 Age 1.04 1.001–1.08 0.045
 D0 haemoglobin concentration 0.51 0.34–0.76 0.001
Reticulocyte dynamics
 D0 haemoglobin concentration −0.320 − 0.420 ─ -0.219 < 0.001
  1. aBy logistic regression, the odds ratio is reported with 95% confidence interval