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Table 4 MICs of 14 antimicrobial agents for 73 TCD isolates by agar dilution method

From: Epidemiology of Clostridium difficile infection in hospitalized adults and the first isolation of C. difficile PCR ribotype 027 in central China

Antimicrobial agent

Breakpoint of resistant

(ug/ml)

MIC (ug/ml)

No. (%) of isolates

MIC50

(ug/ml)

MIC90

(ug/ml)

Range

(ug/ml)

Sensitive

Intermediate

Resistant

Metronidazole

≥ 32

0.25

0.25

≤0.03–1

73 (100)

0 (0)

0 (0)

Piperacillin/tazobactam

≥128/4

4

8

≤0.03–16

73 (100)

0 (0)

0 (0)

Meropenem

≥16

1

2

≤0.03–8

72 (98.6)

1 (1.4)

0 (0)

Tetracycline

≥16

0.25

16

≤0.03–32

54 (74.0)

9 (12.3)

10 (13.7)

Clindamycin

≥8

8

> 128

≤0.03- > 128

27 (37.0)

7 (9.6)

39 (53.4)

Erythromycin

≥8

128

> 128

≤0.03- > 128

28 (38.4)

–

45 (61.6)

Chloramphenicol

≥ 32

4

8

≤0.03–16

72 (98.6)

1 (1.4)

0 (0)

Vancomycin

≥ 32

0.5

1

≤0.03–16

73 (100)

–

0 (0)

Rifampicin

≥ 32

≤0.03

≤0.03

≤0.03–1

73 (100)

–

0 (0)

Levofloxacin

≥8

4

64

≤0.03- > 128

61 (83.6)

–

12 (16.4)

Ciprofloxacin

≥8

8

32

≤0.03- > 128

21 (28.8)

–

52 (71.2)

Moxifloxacin

≥8

2

8

≤0.03–32

64 (87.7)

0 (0)

9 (12.3)

Fusidic acid

> 0.5

0.5

8

≤0.03–16

40 (54.8)

–

33 (45.2)

Linezolid

> 4

2

4

≤0.03–4

73 (100)

–

0 (0)