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Table 6 Prognostic factors associated with prolonged time (≥7 days) taken for temperature normalization in PLA patients

From: Comparison of clinical characteristics and outcomes of pyogenic liver abscess patients < 65 years of age versus ≥ 65 years of age

Variable (N = 332)

Univariate analysis

Multivariate analysis

<  7 days

N = 174

≥ 7 days

N = 158

P value

OR (95% CI)

P value

Age (years; median, range)

57(20–89)

59(18–84)

0.385

  

Gender (Male/Female)

108/66

79/79

0.027

1.767(1.017–3.070)

0.012

Etiologies (n, %)

 Biliary source

64(36.8%)

43(27.2%)

0.063

  

 Portal vein seeding, bowel and/or pelvic pathology

13(7.5%)

16(10.1%)

0.392

  

 Hepatic artery seeding

6(3.4%)

12(7.6%)

0.162

  

 Direct extension

18(10.3%)

21(13.3%)

0.405

  

 Trauma to the liver

7(4.0%)

5(3.2%)

0.676

  

 Cryptogenic infection

65(37.4%)

61(38.6%)

0.814

  

Comorbidities (n, %)

 Smoking

52(29.9%)

38(24.1%)

0.232

  

 Drinking

38(21.8%)

18(11.4%)

0.011

2.849(1.262–6.430)

0.012

 Hypertension

40(23.0%)

29(18.4%)

0.299

  

 Diabetes mellitus

58(33.3%)

48(30.4%)

0.564

  

 Hepatobiliary malignant diseases

19(10.9%)

21(13.3%)

0.507

  

 Cholelithiasis

74(42.5%)

49(31.0%)

0.052

  

 Cirrhosis

10(5.7%)

4(2.5%)

0.145

  

 Viral hepatitis

14(8.0%)

9(5.7%)

0.400

  

Surgery history

 Abdominal surgery history

87(50.0%)

68(43.0%)

0.204

  

  Hepatobiliary surgery

74(42.5%)

55(34.8%)

0.150

  

  Other surgery

13(8.5%)

13(8.2%)

0.798