Table 1 Characteristics of studies included
Name, year | Time of samples collection | Type of study | Region | Inclusion criteria of the studies included | Exclusion criteria of the studies included |
|---|---|---|---|---|---|
Bleeker 2005 | 1995–2002 | Case- control study | Netherlands | Regular male sexual partners of women with CIN and men visiting the outpatient non-STD clinic | Men with a sexually transmitted disease or with anogenital cancer |
Rosenblatt 2004 | 1999–2001 | Case- control study | Brazil | Partners of women having CIN and partners of women without CIN | None |
Rombaldi 2006 | 2003–2004 | Cross- sectional study | Brazil | Male sexual partners of women with CIN | None |
Giraldo 2008 | 2003–2005 | Cross- sectional study | Brazil | Asymptomatic men who were the sexual partners of women who had a histopathological diagnosis of any low-grade squamous intraepithelial lesions (LSIL) | Sexual partners of women with high-grade lesions |
Benevolo 2008 | 2004–2006 | Cross- sectional study | Italy | Italian clinically healthy men, monogamous sexual partners of women affected previously or presently by cervical intraepithelial neoplasia (CIN1 to CIN3) and /or with a positive result of HPV DNA. | Circumcised men and men who reported any previous episode of a sexually transmitted disease. Use of condoms the last 12 months |
Guzman-Esquivel 2009 | 2004–2005 | Case- control study | Mexico | Stable male sexual partners, of women with CIN and male sexual partners of women with normal cervical uterine cytology | Men presenting with penile or genital alterations such as genital herpes pediculosis blenorragia and psoriasis and men who were HIV-positive, receiving antiviral or immuno-modulating treatment and men who had received radiotherapy or chemotherapy. Men whose samples were insufficient or inadequate for DNA extraction or if there had been technical errors during their processing. |
Martin-Ezquerra 2012 | 2006–2007 | Cross- sectional study | Spain | Heterosexual male partners of women, who had been diagnosed with a CIN II or III during the 6 months prior to enrollment | Partners of women with pregnancy and any kind immune-suppression |
Afonso 2013 | 2000–2010 | Cross- sectional study | Brazil | Female patients presenting CIN as well as their male sexual partners (Group I) and asymptomatic couples (Group II) | None |
de Lima Rocha 2012 | N/A | Cross- sectional study | Brazil | Stable male partners (for at least 6 months) of women with cytological or histopathological diagnosis of cervical squamous intraepithelial lesions associated to HPV infection. | None |
Rob 2017 | 2013–2015 | Cross- sectional study | Czech republic | Monogamous male partners of women with histologically verified CIN (grades II-III) or genital warts | Length of the current relationship, intercourse with other sexual partners and HPV vaccination |
Vargas 2016 | 2015 (3 months) | Cross- sectional study | Colombia | Women engaged in a regular relationship and presenting CIN and their sexual partners | None |
Lopez-Diez 2017 | 2013–2015 | Cross- sectional study | Spain | Asymptomatic men, more than 18 years old, not vaccinated against HPV, whose sexual partners (regular sexual intercourse more than 1 year) had presented high grade squamous cervical lesions (CIN II or CIN III in the previous 6 months) | None |