Table 2 Association of CD4 T cell subsets, MFI of CD25 and CD127, Level of immune activation and level of cytotoxicity with absolute CD4 count across the groups
From: Immune signatures for HIV-1 and HIV-2 induced CD4+T cell dysregulation in an Indian cohort
| Â | HIV-1 | HIV-2 | ||||||
|---|---|---|---|---|---|---|---|---|
ART-naïve | ART-receiving | ART-naïve | ART-receiving | |||||
r | P value | r | P value | r | P value | r | P value | |
% Treg cells | −0.6849 | 0.0034 | − 0.2905 | 0.3357 | − 0.8505 | < 0.0001 | −0.6299 | 0.0067 |
% Effector CD4+ T cells | −0.4059 | 0.1188 | −0.5337 | 0.0603 | −0.5541 | 0.0321 | −0.4608 | 0.0627 |
% Naïve/ memory CD4+ T cells | 0.6435 | 0.0071 | 0.4512 | 0.1218 | 0.7379 | 0.0017 | 0.5564 | 0.0204 |
MFI Of CD25 within Tregs | −0.05527 | 0.8389 | 0.4182 | 0.1550 | −0.3825 | 0.1594 | 0.1864 | 0.4738 |
MFI of CD127 within naive/memory CD4+ T cells | −0.2424 | 0.3656 | 0.3901 | 0.1876 | 0.1126 | 0.6895 | 0.4856 | 0.0482 |
% CD4+ HLADR+ CD38+ T cells | −0.7333 | 0.0311 | NA | −0.2857 | 0.3440 | NA | ||
% CD8+ HLADR+ CD38+ T cells | −0.7500 | 0.0255 | NA | −0.3571 | 0.2309 | NA | ||
% CD4+ GrzB+ T cells | 0.8693 | 0.0022 | NA | 0.04945 | 0.8725 | NA | ||
% CD8+ GrzB + T cells | −0.7591 | 0.0149 | NA | −0.3736 | 0.2086 | NA | ||