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Table 1 Baseline characteristics of the study subjects

From: Safety of live attenuated varicella-zoster vaccine in patients with underlying illnesses compared with healthy adults: a prospective cohort study

Characteristics

Healthy adults

(N = 1200)

Patients with underlying illnesses

(N = 300)

Patients with malignancy

(N = 49)

Patients with diabetes mellitus

(N = 180)

Patients with autoimmune diseases

(N = 10)

Patients with chronic renal diseases

(N = 61)

Sex

Male

607 (51%)

188 (63%)*

26 (53%)

120 (67%)*

2 (20%)**

40 (66%)*

Age (y)

Mean ± SD

62.0 ± 8.0

66.0 ± 8.0

71.0 ± 9.0*

65.0 ± 8.0*

61.0 ± 7.0

69.0 ± 8.0*

50–59

530 (44%)

63 (21%)*

3 (6%)*

46 (26%)*

4 (40%)

10 (16%)*

60–69

425 (35%)

129 (43%)

21 (43%)

80 (44%)

4 (40%)

24 (39%)

70+

245 (20%)

108 (36%)

25 (51%)

54 (30%)

2 (20%)

27 (44%)

History of HZ

Present

155 (13%)

49 (16%)

11 (22%)**

28 (16%)

1 (10%)

9 (15%)

Previous vaccination

Present

3 (0.3%)

3 (1%)**

2 (4%)*

1 (1%)

0 (0%)

0 (0%)

White blood cells (/μL)

Mean ± SD

6289 ± 1685

5386 ± 1223

6505 ± 1811

6100 ± 520

5980 ± 1430

HbA1c (%)

Mean ± SD

7.0 ± 1.0

Duration of diabetes mellitus (y)

Mean ± SD

8.0 ± 7.0

Creatinine (mg/dL)

Mean ± SD

0.99 ± 0.15

eGFR (mL/min/1.73 m2)

Mean ± SD

53 ± 4

Dialysis

Present

0 (0%)

  1. Data are expressed as n (%) unless otherwise indicated
  2. HZ Herpes zoster, SD Standard deviation
  3. *P < 0.05, **P < 0.1 (compared with the proportion of subjects among healthy adults)